Deciphering epitranscriptome: modification of mRNA bases provides a new perspective for post-transcriptional regulation of gene expression

S Kumar, T Mohapatra - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Gene regulation depends on dynamic and reversibly modifiable biological and chemical
information in the epigenome/epitranscriptome. Accumulating evidence suggests that …

Plants' epigenetic mechanisms and abiotic stress

M Miryeganeh - Genes, 2021 - mdpi.com
Plants are sessile organisms that need to adapt to constantly changing environmental
conditions. Unpredictable climate change places plants under a variety of abiotic stresses …

Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification

MT Parker, K Knop, AV Sherwood, NJ Schurch… - Elife, 2020 - elifesciences.org
Understanding genome organization and gene regulation requires insight into RNA
transcription, processing and modification. We adapted nanopore direct RNA sequencing to …

A photoregulatory mechanism of the circadian clock in Arabidopsis

X Wang, B Jiang, L Gu, Y Chen, M Mora, M Zhu… - Nature plants, 2021 - nature.com
Cryptochromes (CRYs) are photoreceptors that mediate light regulation of the circadian
clock in plants and animals. Here we show that CRYs mediate blue-light regulation of N6 …

N6‐Methyladenosine mRNA methylation is important for salt stress tolerance in Arabidopsis

J Hu, J Cai, SJ Park, K Lee, Y Li, Y Chen… - The Plant …, 2021 - Wiley Online Library
As the most abundant internal modification of mRNA, N6‐methyladenosine (m6A)
methylation of RNA is emerging as a new layer of epitranscriptomic gene regulation in …

Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis

B Jiang, Z Zhong, L Gu, X Zhang, J Wei, C Ye, G Lin… - Nature Plants, 2023 - nature.com
Light regulates chlorophyll homeostasis and photosynthesis via various molecular
mechanisms in plants. The light regulation of transcription and protein stability of nuclear …

[HTML][HTML] Epigenetic modifications of mRNA and DNA in plants

Z Liang, A Riaz, S Chachar, Y Ding, H Du, X Gu - Molecular Plant, 2020 - cell.com
Advances in the detection and mapping of messenger RNA (mRNA) N 6-methyladenosine
(m 6 A) and 5-methylcytosine (m 5 C), and DNA N 6-methyldeoxyadenosine (6mA) …

RNA methylation in plants: An overview

H Shinde, A Dudhate, US Kadam… - Frontiers in Plant Science, 2023 - frontiersin.org
RNA methylation is an important post-transcriptional modification that influences gene
regulation. Over 200 different types of RNA modifications have been identified in plants. In …

MdMTA‐mediated m6A modification enhances drought tolerance by promoting mRNA stability and translation efficiency of genes involved in lignin deposition and …

N Hou, C Li, J He, Y Liu, S Yu, M Malnoy… - New …, 2022 - Wiley Online Library
Although the N6‐methyladenosine (m6A) modification is the most prevalent RNA
modification in eukaryotes, the global m6A modification landscape and its molecular …

DENA: training an authentic neural network model using Nanopore sequencing data of Arabidopsis transcripts for detection and quantification of N6 …

H Qin, L Ou, J Gao, L Chen, JW Wang, P Hao, X Li - Genome Biology, 2022 - Springer
Abstract Models developed using Nanopore direct RNA sequencing data from in vitro
synthetic RNA with all adenosine replaced by N 6-methyladenosine (m6A) are likely …