Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …

P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …

BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

In the field of targeted drug delivery, the effects of size and morphology of drug nanocarriers
are of great importance and need to be discussed in depth. To be concise, among all the …

Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …

Oral absorption of protein/peptide-loaded nanoparticles is often limited by multiple barriers
of the intestinal epithelium. In addition to mucus translocation and apical endocytosis, highly …

Although solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have
been successfully used as drug delivery systems for about 30 years, the usage of these …

Dual-targeting nanoparticle drug delivery system was developed by conjugating Angiopep
with PEG–PCL nanoparticles (ANG-NP) through bifunctional PEG to overcome the …

Neural stem cells (NSCs) show potential for spinal cord injury (SCI) repair. However, the
current challenge is to direct their differentiation into neurons in the lesion site. It has been …