Dosimetric impact of 3D motion-compensated SPECT reconstruction for SIRT planning

L Vergnaud, A Robert, T Baudier, S Parisse-Di Martino… - EJNMMI physics, 2023 - Springer
Background In selective internal radiation therapy, 99mTc SPECT images are used to
optimize patient treatment planning, but they are affected by respiratory motion. In this study …

How the rigid and deformable image registration approaches affect the absorbed dose estimation using images collected before and after transarterial …

G Della Gala, M Santoro, G Paolani, S Strolin… - Applied Sciences, 2022 - mdpi.com
Background: Transarterial radioembolization (TARE) relies on directly injected 90Y-or
166Ho-loaded microspheres in the hepatic arteries. The activity to be injected is generally …

Development of a scatter correction technique for planar 99mTc-MAA imaging to improve accuracy in lung shunt fraction estimation

N McArdle, S Cournane, J McCavana, J Lucey… - Physica Medica, 2022 - Elsevier
Purpose Prior to 90 Y selective internal radiation therapy (SIRT) treatment, 99m Tc-MAA
scintigraphy imaging is used in the estimation of the lung shunt fraction (LSF). Planar …

Quantitative evaluation of 90Y‐PET/CT and 90Y‐SPECT/CT‐based dosimetry following Yttrium‐90 radioembolization

SC Kappadath, EC Henry, BP Lopez… - Medical …, 2024 - Wiley Online Library
Abstract Background Following yttrium‐90 radioembolization (90Y‐RE), 90Y‐PET/CT and
90Y‐SPECT/CT imaging provide the means to calculate the voxelized absorbed dose …

Dosimetry for 177Lu and 90Y radionuclide therapies through imaging and Monte Carlo simulations

L Vergnaud - 2023 - theses.hal.science
In nuclear medicine, targeted radionuclide therapy (TRT) involves intravenous injection of a
radiopharmaceutical that specifically binds to tumour cells through a selected vector based …

[HTML][HTML] Future trends for patient-specific dosimetry methodology in molecular radiotherapy

J Gustafsson, J Taprogge - Physica Medica, 2023 - Elsevier
Molecular radiotherapy is rapidly expanding, and new radiotherapeutics are emerging. The
majority of treatments is still performed using empirical fixed activities and not tailored for …