This umbrella review is the first to systematically examine psychological trauma as a
transdiagnostic risk factor across psychiatric conditions. We searched Pubmed, Scopus, and …

Bipolar disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic …

Importance Borderline personality disorder (BPD) affects approximately 0.7% to 2.7% of
adults in the US. The disorder is associated with considerable social and vocational …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is an empirical effort to address
limitations of traditional mental disorder diagnoses. These include arbitrary boundaries …

The heterogeneity of cognitive profiles among psychiatric patients has been reported to
carry significant clinical information. However, how to best characterize such cognitive …

Caretakers are often intimidated or alienated by patients with borderline personality disorder
(BPD), compounding the clinical challenges posed by the severe morbidity, high social costs …

Background Overlap in symptom domains particularly in the field of impulsivity and
emotional dysregulation in attention deficit hyperactivity disorder (ADHD) and borderline …

Noncoding variants of presumed regulatory function contribute to the heritability of
neuropsychiatric disease. A total of 2,221 noncoding variants connected to risk for ten …