Key points Quadrupeds express different gaits depending on speed of locomotion. Central
pattern generators (one per limb) within the spinal cord generate locomotor oscillations and …

Neurophysiology is the branch of physiology concerned with understanding the function of
neural systems. Neural engineering (also known as neuroengineering) is a discipline within …

A traumatic spinal injury can destroy cells, irreparably damage axons, and trigger a cascade
of biochemical responses that increase the extent of injury. Although damaged central …

The PyDSTool software environment is designed to develop, simulate, and analyze
dynamical systems models, particularly for biological applications. Unlike the engineering …

In this paper we analyze a closed loop neuromechanical model of locomotor rhythm
generation. The model is composed of a spinal central pattern generator (CPG) and a single …

We compared the activity profiles and synergies of spinal motoneurons recorded during
fictive locomotion evoked in immobilized decerebrate cat preparations by midbrain …

This work presents an in-depth numerical investigation into a hypothesized two-layer central
pattern generator (CPG) that controls mammalian walking and how different parameter …

It is well established that stance duration changes more than swing duration for a given
change in cycle duration. Small variations in cycle duration are also observed at any given …

We present MantisBot, a 28 degree of freedom robot controlled by a high-fidelity neural
simulation. It is modeled after the mantis, with many degrees of freedom, because we intend …

We investigate a simple model for motor pattern generation that combines central pattern
generator (CPG) dynamics with a sensory feedback (FB) mechanism. Our CPG comprises a …