[HTML][HTML] NMR spectroscopy for metabolomics research
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …
three principal analytical techniques used in metabolomics (the other two being gas …
Two‐dimensional J‐resolved NMR spectroscopy: review of a key methodology in the metabolomics toolbox
Abstract One‐dimensional (1D) 1H NMR spectroscopy remains a leading analytical
technology in metabolomics. Advantages of this approach include relatively rapid spectral …
technology in metabolomics. Advantages of this approach include relatively rapid spectral …
[PDF][PDF] Accelerated NMR spectroscopy by using compressed sensing
K Kazimierczuk, VY Orekhov - Angewandte Chemie, 2011 - researchgate.net
There is increased interest in high-resolution, fast multidimensional NMR spectroscopy for
studying molecular structure, interactions, and dynamics. The distinct feature of the …
studying molecular structure, interactions, and dynamics. The distinct feature of the …
Atomic-resolution chemical characterization of (2x)72-kDa tryptophan synthase via four- and five-dimensional 1H-detected solid-state NMR
NMR chemical shifts provide detailed information on the chemical properties of molecules,
thereby complementing structural data from techniques like X-ray crystallography and …
thereby complementing structural data from techniques like X-ray crystallography and …
13C Direct Detected NMR for Challenging Systems
IC Felli, R Pierattelli - Chemical Reviews, 2022 - ACS Publications
Thanks to recent improvements in NMR spectrometer hardware and pulse sequence design,
modern 13C NMR has become a useful tool for biomolecular applications. The complete …
modern 13C NMR has become a useful tool for biomolecular applications. The complete …
Multivalency regulates activity in an intrinsically disordered transcription factor
S Clark, JB Myers, A King, R Fiala, J Novacek… - Elife, 2018 - elifesciences.org
The transcription factor ASCIZ (ATMIN, ZNF822) has an unusually high number of
recognition motifs for the product of its main target gene, the hub protein LC8 (DYNLL1) …
recognition motifs for the product of its main target gene, the hub protein LC8 (DYNLL1) …
Random sampling in multidimensional NMR spectroscopy
K Kazimierczuk, J Stanek… - Progress in nuclear …, 2010 - Elsevier
Nuclear Magnetic Resonance (NMR) is nowadays one of the most efficient spectroscopic
techniques, providing insight into molecular structure and dynamics. The sources of the …
techniques, providing insight into molecular structure and dynamics. The sources of the …
Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin
In sarcomeres, α-actinin cross-links actin filaments and anchors them to the Z-disk. FATZ
(filamin-, α-actinin-, and telethonin-binding protein of the Z-disk) proteins interact with α …
(filamin-, α-actinin-, and telethonin-binding protein of the Z-disk) proteins interact with α …
Unambiguous side-chain assignments for solid-state NMR structure elucidation of Nondeuterated Proteins via a combined 5D/4D side-chain-to-backbone experiment
A Klein, SK Vasa, B Söldner, K Grohe… - The Journal of Physical …, 2022 - ACS Publications
Owing to fast-magic-angle-spinning technology, proton-detected solid-state NMR has been
facilitating the analysis of insoluble, crystalline, sedimented, and membrane proteins …
facilitating the analysis of insoluble, crystalline, sedimented, and membrane proteins …
[HTML][HTML] Sequence context influences the structure and aggregation behavior of a PolyQ tract
Expansions of polyglutamine (polyQ) tracts in nine different proteins cause a family of
neurodegenerative disorders called polyQ diseases. Because polyQ tracts are potential …
neurodegenerative disorders called polyQ diseases. Because polyQ tracts are potential …