A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

The discovery of the Sry gene in 1990 triggered a revolution in our understanding of sex
determination. More recently, advances in non-model organisms have been fuelled by the …

Variation in the TGF-β signaling pathway is emerging as an important mechanism by which
gonadal sex determination is controlled in teleosts. Here we show that amhy, a Y-specific …

In mammals, the transcription factor SRY, encoded by the Y chromosome, is normally
responsible for triggering the indifferent gonads to develop as testes rather than ovaries …

The present review focuses on the roles of estrogens and aromatase (Cyp19a1a), the
enzyme needed for their synthesis, in fish gonadal sex differentiation. Based on the recent …

Not all vertebrates share the familiar system of XX: XY sex determination seen in mammals.
In the chicken and other birds, sex is determined by a ZZ: ZW sex chromosome system …

Four pairs of XX and XY gonads from Nile tilapia were sequenced at four developmental
stages, 5, 30, 90, and 180 days after hatching (dah) using Illumina HiseqTM technology …

Previous studies have equated FOXL2 as a crucial actor in the ovarian differentiation
process in different vertebrate species. Its transcriptional extinction in the polled intersex …

A critical element of successful sexual reproduction is the generation of sexually dimorphic
adult reproductive organs, the testis and ovary, which produce functional gametes …

Doublesex-and Mab-3-related transcription factor-1 (Dmrt1) is an important transcription
factor implicated in early testicular differentiation in vertebrates, but its target genes are …