Many research questions in fields such as personalized medicine, drug screens or systems
biology depend on obtaining consistent and quantitatively accurate proteomics data from …

The question of how genomic information is expressed to determine phenotypes is of central
importance for basic and translational life science research and has been studied by …

Mass spectrometry (MS) based proteomics have achieved a near-complete proteome
coverage in humans and in several other organisms, producing a wealth of information …

Inadequate dosing and incomplete treatment regimens, coupled with the ability of the
tuberculosis bacilli to cause latent infections that are tolerant of currently used drugs, have …

Mass spectrometry is the method of choice for deep and reliable exploration of the (human)
proteome. Targeted mass spectrometry reliably detects and quantifies pre-determined sets …

The ability to reliably and reproducibly measure any protein of the human proteome in any
tissue or cell type would be transformative for understanding systems-level properties as …

Targeted proteomics by selected/multiple reaction monitoring (S/MRM) or, on a larger scale,
by SWATH (sequential window acquisition of all theoretical spectra) MS (mass spectrometry) …

Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is the main
method for high-throughput identification and quantification of peptides and inferred …

Here we describe the use of data-independent acquisition (DIA) on a Q-Exactive mass
spectrometer for the detection and quantification of peptides in complex mixtures using the …

Mycobacterium tuberculosis remains a health concern due to its ability to enter a non-
replicative dormant state linked to drug resistance. Understanding transitions into and out of …