[HTML][HTML] Interpol review of controlled substances 2016–2019
NS Jones, JH Comparin - Forensic science international: synergy, 2020 - Elsevier
This review paper covers the forensic-relevant literature in controlled substances from 2016
to 2019 as a part of the 19th Interpol International Forensic Science Managers Symposium …
to 2019 as a part of the 19th Interpol International Forensic Science Managers Symposium …
Analysis of conventional and nonconventional forensic specimens in drug-facilitated sexual assault by liquid chromatography and tandem mass spectrometry
N Almofti, A Ballesteros-Gómez, S Rubio… - Talanta, 2022 - Elsevier
The incidence of drug-facilitated sexual assault (DFSA) has dramatically increased in the
last decades. Forensic analytical scientists continuously seek new methods and specimens …
last decades. Forensic analytical scientists continuously seek new methods and specimens …
Development of a highly efficient long-acting cocaine hydrolase entity to accelerate cocaine metabolism
It is particularly challenging to develop a truly effective pharmacotherapy for cocaine use
disorder (CUD) treatment. Accelerating cocaine metabolism via hydrolysis at cocaine …
disorder (CUD) treatment. Accelerating cocaine metabolism via hydrolysis at cocaine …
Gender differences in cocaine‐induced hyperactivity and dopamine transporter trafficking to the plasma membrane
As well known, cocaine induces stimulant effects and dopamine transporter (DAT) trafficking
to the plasma membrane of dopaminergic neurons. In the present study, we examined …
to the plasma membrane of dopaminergic neurons. In the present study, we examined …
[HTML][HTML] Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine
Cocaine is a widely abused, hepatotoxic drug without an FDA-approved pharmacotherapy
specific for cocaine addiction or overdose. It is recognized as a promising therapeutic …
specific for cocaine addiction or overdose. It is recognized as a promising therapeutic …
Recovery of dopaminergic system after cocaine exposure and impact of a long‐acting cocaine hydrolase
Dysregulation of dopamine transporters (DAT) within the dopaminergic system is an
important biomarker of cocaine exposure. Depending on cocaine amount in‐taken, one …
important biomarker of cocaine exposure. Depending on cocaine amount in‐taken, one …
Cocaine hydrolase blocks cocaine‐induced dopamine transporter trafficking to the plasma membrane
Cocaine blocks dopamine uptake via dopamine transporter (DAT) on plasma membrane of
neuron cells and, as a result, produces the high and induces DAT trafficking to plasma …
neuron cells and, as a result, produces the high and induces DAT trafficking to plasma …
Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine
In the presence of alcohol, cocaine metabolism produces a number of metabolites, including
three toxic ones (cocaethylene, norcocaine, and norcocaethylene) which are all more toxic …
three toxic ones (cocaethylene, norcocaine, and norcocaethylene) which are all more toxic …
A fast and simple approach for the quantification of 40 illicit drugs, medicines, and pesticides in blood and urine samples by UHPLC‐MS/MS
SC Franco de Oliveira, AD Zucoloto… - Journal of mass …, 2019 - Wiley Online Library
A fast and simple approach to overcome challenges in emergency toxicological analysis,
using ultra‐high performance liquid chromatography–tandem mass spectrometry (UHPLC …
using ultra‐high performance liquid chromatography–tandem mass spectrometry (UHPLC …
Simultaneous determination of cocaine and metabolites in human plasma using solid phase micro-extraction fiber tips C18 and UPLC–MS/MS
LLF Lizot, ACC da Silva, MF Bastiani… - Journal of Analytical …, 2020 - academic.oup.com
The determination of cocaine (COC) and its metabolites ecgonine methyl ester (EME),
benzoylecgonine (BZE), norcocaine (NCOC) and cocaethylene (CE) in human plasma is …
benzoylecgonine (BZE), norcocaine (NCOC) and cocaethylene (CE) in human plasma is …