Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2017 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has continued
development and standardization of methodologies for biomarkers and has provided an …
development and standardization of methodologies for biomarkers and has provided an …
Structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with mild cognitive impairment
G Lombardi, G Crescioli, E Cavedo… - Cochrane Database …, 2020 - cochranelibrary.com
Background Mild cognitive impairment (MCI) due to Alzheimer's disease is the symptomatic
predementia phase of Alzheimer's disease dementia, characterised by cognitive and …
predementia phase of Alzheimer's disease dementia, characterised by cognitive and …
New fluid biomarkers tracking non-amyloid-β and non-tau pathology in Alzheimer's disease
SA Park, SM Han, CE Kim - Experimental & molecular medicine, 2020 - nature.com
Cerebrospinal fluid (CSF) biomarkers based on the core pathological proteins associated
with Alzheimer's disease (AD), ie, amyloid-β (Aβ) and tau protein, are widely regarded as …
with Alzheimer's disease (AD), ie, amyloid-β (Aβ) and tau protein, are widely regarded as …
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease
O Libiger, LM Shaw, MH Watson… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction: Biomarkers that reflect pathologic processes affecting neuronal function during
preclinical and early stages of Alzheimer's disease (AD) are needed to aid drug …
preclinical and early stages of Alzheimer's disease (AD) are needed to aid drug …
Predicting the progression of mild cognitive impairment using machine learning: a systematic, quantitative and critical review
We performed a systematic review of studies focusing on the automatic prediction of the
progression of mild cognitive impairment to Alzheimer's disease (AD) dementia, and a …
progression of mild cognitive impairment to Alzheimer's disease (AD) dementia, and a …
A comprehensive systematic review of CSF proteins and peptides that define Alzheimer's disease
CM Pedrero-Prieto, S García-Carpintero… - Clinical Proteomics, 2020 - Springer
Background During the last two decades, over 100 proteomics studies have identified a
variety of potential biomarkers in CSF of Alzheimer's (AD) patients. Although several reviews …
variety of potential biomarkers in CSF of Alzheimer's (AD) patients. Although several reviews …
Oxidative damage of DNA as early marker of Alzheimer's disease
C Peña-Bautista, T Tirle, M López-Nogueroles… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is the most common cause of dementia, and its characteristic
histopathological hallmarks are neurofibrillary tangles and senile plaques. Among involved …
histopathological hallmarks are neurofibrillary tangles and senile plaques. Among involved …
Cerebrospinal fluid proteomics and biological heterogeneity in Alzheimer's disease: a literature review
KEJ Wesenhagen, CE Teunissen… - Critical reviews in …, 2020 - Taylor & Francis
Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
aggregation of amyloid and tau proteins in the brain. Results from genetic studies suggest …
aggregation of amyloid and tau proteins in the brain. Results from genetic studies suggest …
A targeted proteomic multiplex CSF assay identifies increased malate dehydrogenase and other neurodegenerative biomarkers in individuals with Alzheimer's …
Alzheimer's disease (AD) is the most common cause of dementia. Biomarkers are required
to identify individuals in the preclinical phase, explain phenotypic diversity, measure …
to identify individuals in the preclinical phase, explain phenotypic diversity, measure …
Key inflammatory pathway activations in the MCI stage of Alzheimer's disease
Objective To determine the key inflammatory pathways that are activated in the peripheral
and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer's disease …
and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer's disease …