[HTML][HTML] Complexity of vitamin E metabolism

L Schmölz, M Birringer, S Lorkowski… - World journal of …, 2016 - ncbi.nlm.nih.gov
Bioavailability of vitamin E is influenced by several factors, most are highlighted in this
review. While gender, age and genetic constitution influence vitamin E bioavailability but …

Vitamin E and Alzheimer's disease: what do we know so far?

D Browne, B McGuinness, JV Woodside… - … interventions in aging, 2019 - Taylor & Francis
Vitamin E has been proposed as a potential clinical intervention for Alzheimer's disease
(AD) given the plausibility of its various biological functions in influencing the …

Systematic evaluation of pleiotropy identifies 6 further loci associated with coronary artery disease

TR Webb, J Erdmann, KE Stirrups, NO Stitziel… - Journal of the American …, 2017 - jacc.org
Background: Genome-wide association studies have so far identified 56 loci associated with
risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also …

The effectiveness of vitamin E treatment in Alzheimer's disease

A Lloret, D Esteve, P Monllor, A Cervera-Ferri… - International journal of …, 2019 - mdpi.com
Vitamin E was proposed as treatment for Alzheimer's disease many years ago. However, the
effectiveness of the drug is not clear. Vitamin E is an antioxidant and neuroprotector and it …

Diet-derived circulating antioxidants and risk of coronary heart disease: a Mendelian randomization study

J Luo, S le Cessie, D van Heemst… - Journal of the American …, 2021 - jacc.org
Background Previously, observational studies have identified associations between higher
levels of dietary-derived antioxidants and lower risk of coronary heart disease (CHD) …

An atlas of associations between 14 micronutrients and 22 cancer outcomes: Mendelian randomization analyses

JY Kim, M Song, MS Kim, P Natarajan, R Do, W Myung… - BMC medicine, 2023 - Springer
Background Micronutrients, namely vitamins and minerals, are associated with cancer
outcomes; however, their reported effects have been inconsistent across studies. We aimed …

Circulating levels of micronutrients and risk of infections: a Mendelian randomization study

HM Flatby, A Ravi, JK Damås, E Solligård, T Rogne - BMC medicine, 2023 - Springer
Background Micronutrients play an essential role at every stage of the immune response,
and deficiencies can therefore lead to increased susceptibility to infections. Previous …

Association between circulating vitamin E and ten common cancers: evidence from large-scale Mendelian randomization analysis and a longitudinal cohort study

J Xin, X Jiang, S Ben, Q Yuan, L Su, Z Zhang… - BMC medicine, 2022 - Springer
Background The association between vitamin E and cancer risk has been widely
investigated by observational studies, but the findings remain inconclusive. Here, we aimed …

Antioxidants, minerals and vitamins in relation to Crohn's disease and ulcerative colitis: a Mendelian randomization study

J Chen, X Ruan, S Yuan, M Deng… - Alimentary …, 2023 - Wiley Online Library
Background Evidence for antioxidants, minerals and vitamins in relation to the risk of
Crohn's disease (CD) and ulcerative colitis (UC) is limited and inconsistent. This mendelian …

Vitamin E: regulatory role on signal transduction

JM Zingg - IUBMB life, 2019 - Wiley Online Library
Vitamin E modulates signal transduction pathways by several molecular mechanisms. As a
hydrophobic molecule located mainly in membranes it contributes together with other lipids …