Glioblastoma (GBM) is the most common primary malignant brain tumour in adults. Despite
the combination of novel therapeutical approaches, it remains a deadly malignancy with an …

GBM is the most common primary brain tumor in adults, and the aggressive nature of this
tumor contributes to its extremely poor prognosis. Over the years, the heterogeneous and …

Background Clinical studies have shown that the efficacy of programmed cell death receptor-
1/programmed cell death ligand-1 (PD-1/PD-L1) inhibitors on glioblastoma (GBM) is much …

Glioblastoma is a highly prevalent and aggressive form of primary brain tumor. It represents
approximately 56% of all the newly diagnosed gliomas. Macrophages are one of the major …

The role of macrophages in the growth and the progression of tumors has been extensively
studied in recent years. A large body of data demonstrates that macrophage polarization …

Gliomas are aggressive, primary central nervous system tumours arising from glial cells.
Glioblastomas are the most malignant. They are known for their poor prognosis or median …

Glioblastoma (GB) is the most aggressive and most common malignant primary brain tumor
diagnosed in adults. GB shows a poor prognosis and, unfortunately, current therapies are …

The role of extracellular vesicles in cancer biology has emerged as a focus of the study of
great importance and has been shown to directly influence tumour development in several …

Glioblastoma, formerly known as glioblastoma multiforme (GBM), is the most frequent and
most aggressive brain tumour in adults. The brain is an immunopriviledged organ, and the …

During metabolic reprogramming, glioma cells and their initiating cells efficiently utilized
carbohydrates, lipids and amino acids in the hypoxic lesions, which not only ensured …