Polymers and biopolymers with antiviral activity: potential applications for improving food safety

W Randazzo, MJ Fabra, I Falcó… - … Reviews in Food …, 2018 - Wiley Online Library
Gastroenteritis and hepatitis, caused by human noroviruses (HuNoVs) and hepatitis A virus
(HAV), respectively, are the most common illnesses resulting from the consumption of food …

The role of host glycobiology and gut microbiota in rotavirus and norovirus infection, an update

N Peña-Gil, C Santiso-Bellón… - International journal of …, 2021 - mdpi.com
Rotavirus (RV) and norovirus (NoV) are the leading causes of acute gastroenteritis (AGE)
worldwide. Several studies have demonstrated that histo-blood group antigens (HBGAs) …

Relevance of secretor status genotype and microbiota composition in susceptibility to rotavirus and norovirus infections in humans

J Rodríguez-Díaz, I García-Mantrana, S Vila-Vicent… - Scientific reports, 2017 - nature.com
Host genetic factors, such as histo-blood group antigens (HBGAs), are associated with
susceptibility to norovirus (NoV) and rotavirus (RV) infections. Recent advances point to the …

GII. 4 human norovirus: surveying the antigenic landscape

ML Mallory, LC Lindesmith, RL Graham, RS Baric - Viruses, 2019 - mdpi.com
Human norovirus is the leading cause of viral acute onset gastroenteritis disease burden,
with 685 million infections reported annually. Vulnerable populations, such as children …

NMR experiments shed new light on glycan recognition by human and murine norovirus capsid proteins

R Creutznacher, T Maass, P Ogrissek, G Wallmann… - Viruses, 2021 - mdpi.com
Glycan–protein interactions are highly specific yet transient, rendering glycans ideal
recognition signals in a variety of biological processes. In human norovirus (HuNoV) …

The antigenic topology of norovirus as defined by B and T cell epitope mapping: implications for universal vaccines and therapeutics

JM van Loben Sels, KY Green - Viruses, 2019 - mdpi.com
Human norovirus (HuNoV) is the leading cause of acute nonbacterial gastroenteritis.
Vaccine design has been confounded by the antigenic diversity of these viruses and a …

Conformational occlusion of blockade antibody epitopes, a novel mechanism of GII. 4 human norovirus immune evasion

LC Lindesmith, ML Mallory, K Debbink, EF Donaldson… - MSphere, 2018 - Am Soc Microbiol
Extensive antigenic diversity within the GII. 4 genotype of human norovirus is a major driver
of pandemic emergence and a significant obstacle to development of cross-protective …

Chimeric virus-like particles of human norovirus constructed by structure-guided epitope grafting elicit cross-reactive immunity against both GI. 1 and GII. 4 genotypes

YN Hou, YQ Jin, XF Zhang, F Tang, JW Hou… - Journal of …, 2023 - Am Soc Microbiol
Human norovirus (HuNoV) is the main cause of acute non-bacterial gastroenteritis
worldwide. There is no vaccine currently available to prevent HuNoV infection. HuNoV is a …

Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response

L Su, W Huang, FH Neill, MK Estes, RL Atmar… - npj Vaccines, 2023 - nature.com
Human noroviruses (HuNoV) are the leading cause of acute gastroenteritis worldwide. The
humoral immune response plays an important role in clearing HuNoV infections and …

Feasibility of polyclonal avian immunoglobulins (IgY) as prophylaxis against human norovirus infection

C Artman, N Idegwu, KD Brumfield, K Lai, S Hauta… - Viruses, 2022 - mdpi.com
Background: Human norovirus (HuNoV) is the leading viral cause of diarrhea, with GII. 4 as
the predominant genotype of HuNoV outbreaks globally. However, new genogroup variants …