New research has shown that the development of osteoarthritis (OA) is regulated by different
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …

Osteoarthritis (OA), one of the most common joint diseases, is characterized by fibrosis,
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …

Objective: Osteoarthritis (OA) is a common disease with a complex pathology including
mechanical load, inflammation, and metabolic factors. Chondrocyte ferroptosis contributes to …

Background Osteoarthritis (OA) is the most common degenerative joint disease primarily
characterized by cartilage destruction. The aim of this study was to investigate the role …

Melatonin is an ancient antioxidant. After its initial development in bacteria, it has been
retained throughout evolution such that it may be or may have been present in every species …

There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

Viral infections are dangerous diseases for human health worldwide, which lead to
significant morbidity and mortality each year. Because of their importance and the lack of …

Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …

Palmitic acid (PA), the main component of dietary saturated fat, has been known to increase
in patients with obesity, and PA‐induced lipotoxicity may contribute to obesity‐related male …

Ferroptosis is a novel form of regulated cell death that has a close association with
mitochondrial dysfunction and is characterized by iron overload, the accumulation of …