Genomics of microRNA

VN Kim, JW Nam - TRENDS in Genetics, 2006 - cell.com
Discovered just over a decade ago, microRNA (miRNA) is now recognized as one of the
major regulatory gene families in eukaryotic cells. Hundreds of miRNAs have been found in …

MicroRNAs and their regulatory roles in animals and plants

B Zhang, Q Wang, X Pan - Journal of cellular physiology, 2007 - Wiley Online Library
Abstract microRNAs (miRNAs) are an abundant class of newly identified endogenous non‐
protein‐coding small RNAs. They exist in animals, plants, and viruses, and play an important …

A novel class of small RNAs bind to MILI protein in mouse testes

A Aravin, D Gaidatzis, S Pfeffer, M Lagos-Quintana… - Nature, 2006 - nature.com
Abstract Small RNAs bound to Argonaute proteins recognize partially or fully complementary
nucleic acid targets in diverse gene-silencing processes,,,. A subgroup of the Argonaute …

Clustering and conservation patterns of human microRNAs

Y Altuvia, P Landgraf, G Lithwick, N Elefant… - Nucleic acids …, 2005 - academic.oup.com
MicroRNAs (miRNAs) are∼ 22 nt-long non-coding RNA molecules, believed to play
important roles in gene regulation. We present a comprehensive analysis of the …

Inferring noncoding RNA families and classes by means of genome-scale structure-based clustering

S Will, K Reiche, IL Hofacker, PF Stadler… - PLoS computational …, 2007 - journals.plos.org
The RFAM database defines families of ncRNAs by means of sequence similarities that are
sufficient to establish homology. In some cases, such as microRNAs and box H/ACA …

Approaches to microRNA discovery

E Berezikov, E Cuppen, RHA Plasterk - Nature genetics, 2006 - nature.com
MicroRNAs (miRNAs) are noncoding RNAs that can regulate gene expression. Several
hundred genes encoding miRNAs have been experimentally identified in animals, and …

[HTML][HTML] The developmental miRNA profiles of zebrafish as determined by small RNA cloning

PY Chen, H Manninga, K Slanchev… - Genes & …, 2005 - genesdev.cshlp.org
MicroRNAs (miRNAs) represent a family of small, regulatory, noncoding RNAs that are
found in plants and animals. Here, we describe the miRNA profile of the zebrafish Danio …

The expansion of the metazoan microRNA repertoire

J Hertel, M Lindemeyer, K Missal, C Fried, A Tanzer… - BMC genomics, 2006 - Springer
Background MicroRNAs have been identified as crucial regulators in both animals and
plants. Here we report on a comprehensive comparative study of all known miRNA families …

MicroRNA identification based on sequence and structure alignment

X Wang, J Zhang, F Li, J Gu, T He, X Zhang… - Bioinformatics, 2005 - academic.oup.com
Abstract Motivation: MicroRNAs (miRNA) are∼ 22 nt long non-coding RNAs that are derived
from larger hairpin RNA precursors and play important regulatory roles in both animals and …

Rapid microRNA (miRNA) detection and classification via surface-enhanced Raman spectroscopy (SERS)

JD Driskell, AG Seto, LP Jones, S Jokela… - Biosensors and …, 2008 - Elsevier
microRNAs (miRNA) are recognized as regulators of gene expression during development
and cell differentiation as well as biomarkers of disease. Development of rapid and sensitive …