Astrocytes are the most populous glial cells in the central nervous system (CNS). They are
essential to CNS physiology and play important roles in the maintenance of homeostasis …

Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …

As oligodendrocyte precursor cells (OPCs) are vulnerable to ischemia, their differentiation to
oligodendrocytes (OLG) is impaired in chronic cerebral hypoperfusion. Astrocyte–OLG …

Huntington's disease (HD) is a neurodegenerative genetic disorder caused by a CAG repeat
expansion in the huntingtin gene. HD causes motor, cognitive, and behavioral dysfunction …

An important link between brain aging and a class of growth/survival factors called
neurotrophins has recently been demonstrated. In particular, brain-derived neurotrophic …

Physical activity has been considered an important non-medication intervention in
preserving mnemonic processes during aging. However, how aerobic exercise promotes …

Major depressive disorder is one of the most common neuropsychiatric diseases and it is a
global public health problem that leads to disabilities. Currently, there is a growing need to …

Excessive exercise leads to body fatigue and destroys the balance of the oxidation/oxidation
resistance system in the body, thus damaging the central nervous system and reducing …

Neurodegenerative disorders account for a high proportion of neurological diseases that
significantly threaten public health worldwide. Various factors are involved in the …

Objective: Cerebral ischemia is accompanied by damage and death of a significant number
of neurons due to glutamate excitotoxicity with subsequent a global increase of cytosolic …