Current studies on molecular mechanisms of insulin resistance

J Pei, B Wang, D Wang - Journal of Diabetes Research, 2022 - Wiley Online Library
Diabetes is a metabolic disease that raises the risk of microvascular and neurological
disorders. Insensitivity to insulin is a characteristic of type II diabetes, which accounts for 85 …

[HTML][HTML] Nutrigenomics in regulating the expression of genes related to type 2 diabetes mellitus

K Felisbino, JG Granzotti, L Bello-Santos… - Frontiers in …, 2021 - frontiersin.org
Nutrigenomics is the study of the gene-nutrient interaction and it indicates that some
nutrients, called bioactive compounds, can mold the genetic expression or change the …

[HTML][HTML] Biomedical aspects of beta-glucan on glucose metabolism and its role on primary gene PIK3R1

S Chakraborty, VD Rajeswari - Journal of Functional Foods, 2022 - Elsevier
Diabetes mellitus, one of the major metabolic threats to human health has elevated
drastically all along the twenty-first century. Insulin that is released by beta-cells of the …

[HTML][HTML] An integrative pharmacology-based approach for evaluating the potential effects of purslane seed in diabetes mellitus treatment using UHPLC-LTQ-orbitrap …

J Hou, X Zhou, P Wang, C Zhao, Y Qin, F Liu… - Frontiers in …, 2021 - frontiersin.org
Portulaca oleracea L., known as the “vegetable for long life,” is an annual succulent herb
that is widely distributed worldwide. Many clinical and experimental studies have …

[HTML][HTML] Genome-wide DNA methylation analysis in Chinese Chenghua and Yorkshire pigs

K Wang, P Wu, S Wang, X Ji, D Chen, A Jiang… - BMC Genomic …, 2021 - Springer
Abstract Background The Chinese Chenghua pig (CHP) is a typical Chinese domestic fatty
pig breed with superior meat quality characteristics, while the Yorkshire pig (YP) has the …

[HTML][HTML] Mosaic loss of the Y chromosome in human neurodegenerative and oncological diseases

IL Kuznetsova, LI Uralsky, TV Tyazhelova… - Vavilov Journal of …, 2023 - ncbi.nlm.nih.gov
The development of new biomarkers for prediction and early detection of human diseases,
as well as for monitoring the response to therapy is one of the most relevant areas of modern …

[HTML][HTML] Establishment and verification of a gene signature for diagnosing type 2 diabetics by WGCNA, LASSO analysis, and in vitro experiments

H Shao, Y Zhang, Y Liu, Y Yang, X Tang… - BioMed Research …, 2022 - ncbi.nlm.nih.gov
Objective The incidence and prevalence of type 2 diabetes are increasing with age.
Nevertheless, there is lack of sensitive diagnostic tools and effective therapeutic regimens …

[HTML][HTML] Molecular determination of mirRNA-126 rs4636297, phosphoinositide-3-kinase regulatory subunit 1-gene variability rs7713645, rs706713 (Tyr73Tyr) …

R Mir, I Elfaki, FMA Duhier, MA Alotaibi… - Journal of Personalized …, 2021 - mdpi.com
Type 2 diabetes is a metabolic disease characterized by elevated blood sugar. It has serious
complications and socioeconomic impact. The MicroRNAs are short single-stranded and …

[HTML][HTML] Veratrilla baillonii Franch Ameliorates Diabetic Liver Injury by Alleviating Insulin Resistance in Rats

ZH Zhang, J Li, J Li, Z Ma, XJ Huang - Frontiers in Pharmacology, 2021 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is a complex and polygenic disorder with diverse
complications. Veratrilla baillonii Franch (V. baillonii) has been applied in the intervention …

[HTML][HTML] Theoretical investigation of the pathway-based network of type 2 diabetes mellitus-related genes

XY Zhang, TY He, CY Xu, KF Cao, XS Zhang - The European Physical …, 2023 - Springer
Complex network is an effective approach to studying the characteristics and interactions of
complex systems, which can be used to analyze the core functions and global behavior of …