Since the introduction of insulin almost a century ago, more than 80 peptide drugs have
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …

RNA interference mediated by small interfering RNAs (siRNAs) has been exploited for the
development of therapeutics. siRNAs can be a powerful therapeutic tool because the …

For a blood-borne cancer therapeutic agent to be effective, it must cross the blood vessel
wall to reach cancer cells in adequate quantities, and it must overcome the resistance …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent
neurodegenerative diseases, affecting millions and costing billions each year in the United …

Today, bio-medical efforts are entering the subcellular level, which is witnessed with the fast-
developing fields of nanomedicine, nanodiagnostics and nanotherapy in conjunction with …

The blood-brain barrier (BBB) is a dynamic structure that functions as a gatekeeper,
reflecting the unique requirements of the brain. In this review, following a brief historical …

The blood brain barrier (BBB) presents a formidable challenge to the delivery of drugs into
the brain. Several strategies aim to overcome this obstacle and promote efficient and …

The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …

The blood‐brain barrier (BBB) is a semipermeable and extremely selective system in the
central nervous system of most vertebrates, that separates blood from the brain's …

Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …