Microfluidic devices for bioapplications

LY Yeo, HC Chang, PPY Chan, JR Friend - small, 2011 - Wiley Online Library
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …

Microfabrication meets microbiology

DB Weibel, WR DiLuzio, GM Whitesides - Nature Reviews Microbiology, 2007 - nature.com
This Review summarizes methods for constructing systems and structures at micron or
submicron scales that have applications in microbiology. These tools make it possible to …

Scanning electrochemical microscopy

FRF Fan, B Liu, J Mauzeroll - Handbook of electrochemistry, 2007 - Elsevier
Publisher Summary The chapter discusses various techniques and applications of scanning
electrochemical microscopy (SECM), one of the scanning probe microscopies (SPM) in …

Merging microfluidics with microarray-based bioassays

C Situma, M Hashimoto, SA Soper - Biomolecular engineering, 2006 - Elsevier
Microarray technologies provide powerful tools for biomedical researchers and medicine,
since arrays can be configured to monitor the presence of molecular signatures in a highly …

Advances in the application of scanning electrochemical microscopy to bioanalytical systems

WS Roberts, DJ Lonsdale, J Griffiths… - Biosensors and …, 2007 - Elsevier
Scanning electrochemical microscopy (SECM) is a powerful surface characterisation
technique that allows for the electrochemical profiling of surfaces with sub micrometer …

Challenges and approaches to studying pore-forming proteins

JT Benton, C Bayly-Jones - Biochemical Society Transactions, 2021 - portlandpress.com
Pore-forming proteins (PFPs) are a broad class of molecules that comprise various families,
structural folds, and assembly pathways. In nature, PFPs are most often deployed by their …

Electrochemical monitoring of cellular signal transduction with a secreted alkaline phosphatase reporter system

Y Torisawa, N Ohara, K Nagamine, S Kasai… - Analytical …, 2006 - ACS Publications
Electrochemical monitoring of cellular signal transduction under three-dimensional (3-D) cell
culture conditions has been demonstrated by combining cell-based microarrays with a …

Electrophoretic cell manipulation and electrochemical gene-function analysis based on a yeast two-hybrid system in a microfluidic device

T Yasukawa, K Nagamine, Y Horiguchi… - Analytical …, 2008 - ACS Publications
A novel microfluidic device with an array of analytical chambers was developed in order to
perform single-cell-based gene-function analysis. A series of analytical processes was …

Control of the ZnO nanowires nucleation site using microfluidic channels

SH Lee, HJ Lee, D Oh, SW Lee, H Goto… - The Journal of …, 2006 - ACS Publications
We report on the growth of uniquely shaped ZnO nanowires with high surface area and
patterned over large areas by using a poly (dimethylsiloxane)(PDMS) microfluidic channel …

Measurement of gene expression from single adherent cells and spheroids collected using fast electrical lysis

Y Nashimoto, Y Takahashi, T Yamakawa… - Analytical …, 2007 - ACS Publications
The cytosol of a single adherent cell was collected by the electrical cell lysis method with a
Pt-ring capillary probe, and the cellular messenger RNA (mRNA) was analyzed at a single …