Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism
The gut microbiota influences the health of the host, especially with regard to gut immune
homeostasis and the intestinal immune response. In addition to serving as a nutrient …
homeostasis and the intestinal immune response. In addition to serving as a nutrient …
Neurotransmitters: The critical modulators regulating gut–brain axis
R Mittal, LH Debs, AP Patel, D Nguyen… - Journal of cellular …, 2017 - Wiley Online Library
Neurotransmitters, including catecholamines and serotonin, play a crucial role in
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …
A tissue-like neurotransmitter sensor for the brain and gut
Neurotransmitters play essential roles in regulating neural circuit dynamics both in the
central nervous system as well as at the peripheral, including the gastrointestinal tract …
central nervous system as well as at the peripheral, including the gastrointestinal tract …
The mechanism of secretion and metabolism of gut-derived 5-hydroxytryptamine
N Liu, S Sun, P Wang, Y Sun, Q Hu… - International journal of …, 2021 - mdpi.com
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
Serotonin signalling in the gut—functions, dysfunctions and therapeutic targets
GM Mawe, JM Hoffman - Nature reviews Gastroenterology & hepatology, 2013 - nature.com
Abstract Serotonin (5-HT) has been recognized for decades as an important signalling
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …
Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine
BB Williams, AH Van Benschoten, P Cimermancic… - Cell host & …, 2014 - cell.com
Several recent studies describe the influence of the gut microbiota on host brain and
behavior. However, the mechanisms responsible for microbiota-nervous system interactions …
behavior. However, the mechanisms responsible for microbiota-nervous system interactions …
Tryptophan metabolites along the microbiota-gut-brain axis: an interkingdom communication system influencing the gut in health and disease
A Bosi, D Banfi, M Bistoletti… - International Journal of …, 2020 - journals.sagepub.com
The 'microbiota-gut-brain axis' plays a fundamental role in maintaining host homeostasis,
and different immune, hormonal, and neuronal signals participate to this interkingdom …
and different immune, hormonal, and neuronal signals participate to this interkingdom …
The diverse metabolic roles of peripheral serotonin
Abstract Serotonin (5-hydroxytryptamine or 5-HT) is a multifunctional bioamine with
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …
The serotonin signaling system: from basic understanding to drug development for functional GI disorders
MD Gershon, J Tack - Gastroenterology, 2007 - Elsevier
Serotonin is an important gastrointestinal signaling molecule. It is a paracrine messenger
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …
[HTML][HTML] Modulation of gut microbiota composition by serotonin signaling influences intestinal immune response and susceptibility to colitis
Background & Aims Serotonin (5-hydroxytryptamine [5-HT]) is synthesized mainly within
enterochromaffin (EC) cells in the gut, and tryptophan hydroxylase 1 (Tph1) is the rate …
enterochromaffin (EC) cells in the gut, and tryptophan hydroxylase 1 (Tph1) is the rate …