Role of neuropeptides in inflammatory bowel disease

KJ Gross, C Pothoulakis - Inflammatory bowel diseases, 2007 - academic.oup.com
Inflammatory bowel disease (IBD) is a chronic, relapsing condition involving complex
interactions between genes and the environment. The mechanisms triggering the initial …

Immunomodulatory properties of substance P: the gastrointestinal system as a model

HW Koon, C Pothoulakis - Annals of the New York Academy of …, 2006 - Wiley Online Library
Communication between nerves and immune and inflammatory cells of the small and large
intestine plays a major role in the modulation of several intestinal functions, including …

Lactobacillus fermentum species ameliorate dextran sulfate sodium-induced colitis by regulating the immune response and altering gut microbiota

YJ Jang, WK Kim, DH Han, K Lee, G Ko - Gut microbes, 2019 - Taylor & Francis
We evaluated immunometabolic functions of novel Lactobacillus fermentum strains (KBL374
and KBL375) isolated from feces of healthy Koreans. The levels of inflammatory cytokines …

[HTML][HTML] Modulation of intestinal inflammation by yeasts and cell wall extracts: strain dependence and unexpected anti-inflammatory role of glucan fractions

S Jawhara, K Habib, F Maggiotto, G Pignede… - 2012 - journals.plos.org
Yeasts and their glycan components can have a beneficial or adverse effect on intestinal
inflammation. Previous research has shown that the presence of Saccharomyces cerevisiae …

[HTML][HTML] Sex differences in gut fermentation and immune parameters in rats fed an oligofructose-supplemented diet

P Shastri, J McCarville, M Kalmokoff, SPJ Brooks… - Biology of sex …, 2015 - Springer
Background Mechanistic data to support health claims is often generated using rodent
models, and the influence of prebiotic supplementation has largely been evaluated using …

Saccharomyces boulardii decreases inflammation and intestinal colonization by Candida albicans in a mouse model of chemically-induced colitis

S Jawhara, D Poulain - Medical Mycology, 2007 - academic.oup.com
The present study was designed to investigate the effects of Saccharomyces boulardii on
inflammation and intestinal colonization by Candida albicans in a BALB/c mouse model of …

Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome

A Rijnierse, FP Nijkamp, AD Kraneveld - Pharmacology & therapeutics, 2007 - Elsevier
Mast cells are well known as versatile cells capable of releasing and producing a variety of
inflammatory mediators upon activation and are often found in close proximity of neurons. In …

[HTML][HTML] Methionine restriction on oxidative stress and immune response in dss-induced colitis mice

G Liu, L Yu, J Fang, CAA Hu, J Yin, H Ni, W Ren… - Oncotarget, 2017 - ncbi.nlm.nih.gov
A strong correlation exists between inflammatory bowel disease (IBD) and oxidative stress
involving alterations of several key signaling pathways. It is known that methionine promotes …

[HTML][HTML] The role of T cell PPAR γ in mice with experimental inflammatory bowel disease

AJ Guri, SK Mohapatra, WT Horne, R Hontecillas… - BMC …, 2010 - Springer
Background Peroxisome proliferator-activated receptor γ (PPAR γ) is a nuclear receptor
whose activation has been shown to modulate macrophage and T cell-mediated …

Administration of Lactobacillus paracasei strains improves immunomodulation and changes the composition of gut microbiota leading to improvement of colitis in mice

WK Kim, YJ Jang, B Seo, DH Han, SJ Park… - Journal of Functional …, 2019 - Elsevier
We confirmed that Lactobacillus paracasei (L. paracasei) strains (KBL382, 384, 385)
exhibited strong protective effects in an in vivo dextran sodium sulfate-induced colitis model …