[HTML][HTML] Topical use of tranexamic acid: are there concerns for cytotoxicity?
I Gkiatas, AP Kontokostopoulos… - World journal of …, 2022 - ncbi.nlm.nih.gov
Tranexamic acid (TXA) has revolutionized modern blood management in orthopaedic
surgery, especially in total joint arthroplasty, by significantly reducing blood loss and …
surgery, especially in total joint arthroplasty, by significantly reducing blood loss and …
The effect of tranexamic acid for visualization on pump pressure and visualization during arthroscopic rotator cuff repair: an anonymized, randomized controlled trial
TA Nicholson, JM Kirsch, R Churchill… - Journal of Shoulder and …, 2022 - Elsevier
Background Tranexamic acid (TXA) has been used surgically to decrease blood loss. The
ability of TXA to improve arthroscopic visualization and allow for reduction in pump pressure …
ability of TXA to improve arthroscopic visualization and allow for reduction in pump pressure …
Cytotoxicity of tranexamic acid to tendon and bone in vitro: Is there a safe dosage?
Introduction Tranexamic acid (TXA) has been shown to be effective at reducing peri-
operative blood loss and haemarthrosis in arthroplasty and arthroscopic soft tissue …
operative blood loss and haemarthrosis in arthroplasty and arthroscopic soft tissue …
Tranexamic Acid Attenuates the Progression of Posttraumatic Osteoarthritis in Mice
W Xie, S Jiang, A Donat, PR Knapstein… - … American Journal of …, 2024 - journals.sagepub.com
Background: Posttraumatic osteoarthritis (OA) is a common disorder associated with a high
socioeconomic burden, particularly in young, physically active, and working patients …
socioeconomic burden, particularly in young, physically active, and working patients …
Tranexamic acid in combination with vancomycin or gentamicin has a synergistic effect against Staphylococci
A Benjumea, M Díaz-Navarro, R Hafian… - Frontiers in …, 2022 - frontiersin.org
Background Tranexamic acid (TXA) is an antifibrinolytic agent applied in orthopedic surgery
and has been proven to reduce post-surgery infection rates. We previously showed that TXA …
and has been proven to reduce post-surgery infection rates. We previously showed that TXA …
Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint …
Background Dysregulated inflammatory responses are implicated in the pathogenesis of
joint stiffness and arthrofibrosis following total knee arthroplasty (TKA). The purpose of this …
joint stiffness and arthrofibrosis following total knee arthroplasty (TKA). The purpose of this …
Rapamycin-loaded Poly (lactic-co-glycolic) acid nanoparticles: Preparation, characterization, and in vitro toxicity study for potential intra-articular injection
E Pape, M Parent, A Pinzano, A Sapin-Minet… - International Journal of …, 2021 - Elsevier
Osteoarthritis (OA) is the most common degenerative joint disease. Rapamycin is a potential
candidate for OA treatment by increasing the autophagy process implicated in its …
candidate for OA treatment by increasing the autophagy process implicated in its …
Validation of the antibacterial effect of topically applied tranexamic acid using in vitro and in vivo models
A Benjumea, M Díaz-Navarro… - Frontiers in …, 2024 - frontiersin.org
Background Several studies have shown that tranexamic acid (TXA), an antifibrinolytic,
reduces postoperative infection rates. Recent in vitro research showed that TXA alone and …
reduces postoperative infection rates. Recent in vitro research showed that TXA alone and …
Cytotoxicity and effect of topical application of tranexamic acid on human fibroblast in spine surgery
F Wang, SG Wang, Q Yang, LP Nan, TC Cai, DS Wu… - World Neurosurgery, 2021 - Elsevier
Objective In spinal surgery, considerable blood loss is increasingly treated with the local
application of tranexamic acid (TXA). However, little is known about its cytotoxicity and effect …
application of tranexamic acid (TXA). However, little is known about its cytotoxicity and effect …
Topical administration of tranexamic acid reduces postoperative blood loss and inflammatory response in knee arthroscopic arthrolysis: a retrospective comparative …
J Li, M You, L Yao, W Fu, Q Li, G Chen, X Tang… - BMC musculoskeletal …, 2023 - Springer
Background Knee arthroscopic arthrolysis serves as an effective treatment for knee
arthrofibrosis. However, hemarthrosis is the most common complication in arthroscopic …
arthrofibrosis. However, hemarthrosis is the most common complication in arthroscopic …