Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

NN Keum, E Giovannucci - Nature reviews Gastroenterology & …, 2019 - nature.com
Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the
second leading cause of cancer death. Arising through three major pathways, including …

The role of calcium and vitamin D dietary intake on risk of colorectal cancer: Systematic review and meta-analysis of case–control studies

JF Lopez-Caleya, L Ortega-Valín… - Cancer Causes & …, 2022 - Springer
Purpose The aim of this study is to analyze the current evidence about the relationships
between calcium/vitamin D and CRC based on case–control studies according to sex, tumor …

[HTML][HTML] PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain

M Wen, Y Cao, B Wu, T Xiao, R Cao, Q Wang… - Nature …, 2021 - nature.com
The cytoplasmic domain of PD-L1 (PD-L1-CD) regulates PD-L1 degradation and stability
through various mechanism, making it an attractive target for blocking PD-L1-related cancer …

[HTML][HTML] Time trends of colorectal cancer incidence and associated lifestyle factors in South Korea

H Khil, SM Kim, SE Hong, HM Gil, E Cheon, DH Lee… - Scientific reports, 2021 - nature.com
Abstract Worldwide, South Korea had the second highest incidence rates of colorectal
cancer (CRC) in 2018. To inform public health policy to prevent CRC, we aimed to identify …

Rising incidence and impact of early‐onset colorectal cancer in the Asia‐Pacific with higher mortality in females from Southeast Asia: a global burden analysis from …

P Danpanichkul, P Moolkaew… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Aim Early‐onset colorectal cancer (CRC) is a growing global
health concern, especially in the Asia‐Pacific region. However, comprehensive research on …

Dietary intakes of calcium, iron, magnesium, and potassium elements and the risk of colorectal cancer: a meta-analysis

Y Meng, J Sun, J Yu, C Wang, J Su - Biological trace element research, 2019 - Springer
The purpose of this study was to analyze the existing studies and to investigate the
relationship between the risk of colorectal cancer (CRC) and intakes of four individual …

Colon cancer: what we eat

P Pan, J Yu, LS Wang - Surgical Oncology Clinics, 2018 - surgonc.theclinics.com
Materials and methods The authors conducted a PubMed search for human studies
published up to 2017, using the key words—colorectal cancer, diet, nutrition, and …

Relationship between serum vitamin D and calcium levels and vitamin D receptor gene polymorphisms in colorectal cancer

AB Al-Ghafari, KS Balamash… - BioMed Research …, 2019 - Wiley Online Library
Background. Many epidemiological studies have shown that vitamin D deficiency is
associated with various types of human cancers. The biological action of vitamin D and its …

Additively protective effects of vitamin D and calcium against colorectal adenoma incidence, malignant transformation and progression: a systematic review and meta …

D Huang, S Lei, Y Wu, M Weng, Y Zhou, J Xu, D Xia… - Clinical Nutrition, 2020 - Elsevier
Background Colorectal cancer (CRC) exhibits a linear progression from normal colonic
epithelium, adenoma initiation, carcinoma transformation and even to metastasis. Diet …

[HTML][HTML] The relationship between nut intake and risk of colorectal cancer: a case control study

J Lee, A Shin, JH Oh, J Kim - Nutrition journal, 2018 - Springer
Background Nut consumption is known to reduce the risk of obesity, diabetes mellitus, and
cardiovascular disease. However, in previous studies, portion sizes and categories of nut …