Peripheral nerve conduit: materials and structures

S Houshyar, A Bhattacharyya… - ACS chemical …, 2019 - ACS Publications
Peripheral nerve injuries (PNIs) are the most common injury types to affect the nervous
system. Restoration of nerve function after PNI is a challenging medical issue. Extended …

Recent progress in the manipulation of biochemical and biophysical cues for engineering functional tissues

B Bakhshandeh, N Ranjbar, A Abbasi… - Bioengineering & …, 2023 - Wiley Online Library
Tissue engineering (TE) is currently considered a cutting‐edge discipline that offers the
potential for developing treatments for health conditions that negatively affect the quality of …

Application of conductive PPy/SF composite scaffold and electrical stimulation for neural tissue engineering

Y Zhao, Y Liang, S Ding, K Zhang, H Mao, Y Yang - Biomaterials, 2020 - Elsevier
Electrical stimulation (ES) with conductive polymers can dramatically enhance neurite
outgrowth and promote neural regeneration. However, besides ES, the practical …

Articulation inspired by nature: a review of biomimetic and biologically active 3D printed scaffolds for cartilage tissue engineering

DG O'Shea, CM Curtin, FJ O'Brien - Biomaterials Science, 2022 - pubs.rsc.org
In the human body, articular cartilage facilitates the frictionless movement of synovial joints.
However, due to its avascular and aneural nature, it has a limited ability to self-repair when …

Nerve-specific extracellular matrix hydrogel promotes functional regeneration following nerve gap injury

T Meder, T Prest, C Skillen, L Marchal… - NPJ Regenerative …, 2021 - nature.com
Nerve transection requires surgical intervention to restore function. The standard of care
involves coaptation when a tension-free repair is achievable, or interposition of a graft or …

Gene delivery of chitosan-graft-polyethyleneimine vectors loaded on scaffolds for nerve regeneration

Y Wang, Y Li, Z Huang, B Yang, N Mu, Z Yang… - Carbohydrate …, 2022 - Elsevier
As an important transcription factor, c-Jun could upregulate growth factors expression in
Schwann cells (SCs). Arginine-Glycine-Aspartate (RGD)-functionalized chitosan-graft …

Nucleic acid therapies for CNS diseases: pathophysiology, targets, barriers, and delivery strategies

S Padmakumar, A D'Souza, NN Parayath… - Journal of Controlled …, 2022 - Elsevier
Nucleic acid therapeutics have emerged as one of the very advanced and efficacious
treatment approaches for debilitating health conditions, including those diseases affecting …

[HTML][HTML] Electrostimulation via a 3D-printed, biomimetic, neurotrophic, electroconductive scaffold for the promotion of axonal regrowth after spinal cord injury

LM Leahy, I Woods, J Gutierrez-Gonzalez, J Maughan… - Materials Today, 2024 - Elsevier
Spinal cord injury (SCI) is a devastating neurotrauma, affecting 250,000 to 500,000 people
annually, and typically results in paralysis. Electrostimulation can promote neuronal growth …

Polysaccharide-based materials created by physical processes: from preparation to biomedical applications

PR Souza, AC de Oliveira, BH Vilsinski, MJ Kipper… - Pharmaceutics, 2021 - mdpi.com
Polysaccharide-based materials created by physical processes have received considerable
attention for biomedical applications. These structures are often made by associating …

Fabrication of poly (sarcosine), poly (ethylene glycol), and poly (lactic-co-glycolic acid) polymeric nanoparticles for cancer drug delivery

S Bhattacharya - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
The most significant advantage of polymeric nanoparticles is their systematic and target
specific drug delivery properties. These polymeric nanoparticles have the potential to …