Osteocytes form over 90% of the bone cells and are postulated to be mechanosensors
responsible for regulating the function of osteoclasts and osteoblasts in bone modeling and …

During bone remodelling, bone cells are thought to add and remove tissue at sites with high
and low loading, respectively. To predict remodelling, it was proposed that bone is removed …

The main motivation for “hierarchical biomechanics” is that the wide variability of mechanical
properties encountered at the macroscopic scale may be traced back to just a few …

Osteochondral (OC) defects usually involve the damage of both the cartilage and its
underneath subchondral bone. In recent years, tissue engineering (TE) has become the …

A lower limb-pelvis finite element (FE) model with active three-dimensional (3D) muscles
was developed in this study for biomechanical analysis of human body. The model geometry …

Objective To investigate the relevance of the human vertebral endplate poromechanics on
the fluid and metabolic transport from and to the intervertebral disc (IVD) based on educated …

The micro-architecture of cancellous bone is considered a major determinant of the fracture
risk. Yet, if morphometry tells about alterations of the trabecular network, its elastic behaviour …

Due to their advantages in applicability, patient-specific (CAD/CAM) reconstruction plates
are increasingly used in fibula free flap mandible reconstruction. In addition, recently …

Functional adaptation of the femur has been studied extensively by embedding remodelling
algorithms in finite element models, with bone commonly assumed to have isotropic material …

Metastatic bone disease occurs in 70–80% of advanced breast cancer patients and bone
tissue is accepted to have attractive physical properties that facilitate cancer cell attraction …