Multi-dimensional liquid chromatography (MD-LC) continues to gain in popularity for
applications where conventional one-dimensional liquid chromatography is insufficient to …

Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Enantioselective chromatography has been the preferred technique for the determination of
enantiomeric excess across academia and industry. Although sequential multicolumn …

The technique of two-dimensional high-performance liquid chromatography has managed to
gain the recognition it deserves thanks to the advantages of satisfactory separations it can …

This work presents an advanced analytical platform for untargeted enantioselective amino
acid analysis (eAAA) by comprehensive achiral× chiral 2D-LC hyphenated to ESI-QTOF …

Several oxylipins are regulators of inflammation. They are formed by enzymes such as
lipoxygenases or cyclooxygenases, but also stereorandomly by autoxidation. Reversed …

Metabolomics strives to capture the entirety of the metabolites in a biological system by
comprehensive analysis, often by liquid chromatography hyphenated to mass spectrometry …

Despite the rapid development of liquid chromatography (LC) in recent decades, it remains
a challenge to achieve the desired chromatographic separation of complex matrices using a …

Deep eutectic solvents (DESs) are emerging as potential candidates as additives/modifiers
in chiral electrokinetic chromatography (EKC). However, the true role of DESs in the chiral …

A multiple heart-cutting (mLC-LC) two-dimensional HPLC-UV achiral–chiral method for the
direct analysis of branched-chain amino acids (BCAAs) in food supplements under …