The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

Metabolic and haemodynamic perturbations and their interaction drive the development of
diabetic kidney disease (DKD) and its progression towards end stage renal disease (ESRD) …

The vascular and the nervous system are responsible for oxygen, nutrient, and information
transfer and thereby constitute highly important communication systems in higher …

Nogo-A is an important axonal growth inhibitor in the adult and developing CNS. In vitro,
Nogo-A has been shown to inhibit migration and cell spreading of neuronal and …

Nogo‐B receptor (NgBR) was identified as a specific receptor for binding Nogo‐B and is
essential for the stability of Niemann‐Pick type C2 protein (NPC2) and NPC2‐dependent …

A central question in neural tissue engineering is how the tissue-engineered nerve (TEN)
translates detailed transcriptional signals associated with peripheral nerve regeneration into …

Chemotherapy can improve the prognosis and overall survival of breast cancer patients, but
chemoresistance continues a major problem in clinical. Most breast cancer is estrogen …

Nogo-B receptor (NgBR) plays fundamental roles in regulating angiogenesis, vascular
development, and the epithelial-mesenchymal transition (EMT) of cancer cells. However, the …

Endothelial Progenitor Cells (EPCs) can actively participate in revascularization in oxygen-
induced retinopathy (OIR). Yet the mechanisms responsible for their dysfunction is unclear …

The loss function of cerebral cavernous malformation (CCM) genes leads to most CCM
lesions characterized by enlarged leaking vascular lesions in the brain. Although we …