Peritoneal dialysis (PD) is associated with functional and structural changes of the
peritoneal membrane. In this review we describe factors contributing to peritoneal tissue …

Peritoneal dialysis (PD) solutions using glucose as osmotic agent have been used for more
than two decades as effective treatment for patients with end-stage renal disease. Although …

Reactive oxygen species amplify protein kinase C signaling in high glucose-induced
fibronectin expression by human peritoneal mesothelial cells. Background We previously …

Diabetic retinopathy (DR) is a common complication of diabetes that causes severe visual
impairment globally. The pathogenesis of DR is related to oxidative stress and chronic …

Diabetic retinopathy (DR) is a disease that causes visual deficiency owing to vascular
leakage or abnormal angiogenesis. Pericyte apoptosis is considered one of the main …

Angiotensin II induces fibronectin expression in human peritoneal mesothelial cells via
ERK1/2 and p38 MAPK. Background The renin-angiotensin system has been implicated in …

Introduction Diabetes mellitus emerges as a global health crisis and is related to the
development of neurodegenerative diseases. Microglia, a population of macrophages‐like …

Abstract Syndecan‐1 (Sdc1) and its endo‐beta‐d‐glucuronidase heparanase (HPSE) are
implicated in maintenance of intestinal epithelial barrier (IEB), but their alterations and roles …

Background Diabetes mellitus is linked to pancreatic cancer. We hypothesized a role for
pancreatic stellate cells (PSC) in the hyperglycemia induced deterioration of pancreatic …

Atheroma formation involves the movement of vascular smooth muscle cells (VSMC) into the
subendothelial space. The aim of this study was to determine the involvement of PI3K and …