MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

Methodological breakthroughs over the past four decades have repeatedly revolutionized
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …

高通量测序技术是DNA 测序发展历程的一个里程碑, 它为现代生命科学研究提供了前所未有的
机遇. 详细介绍了以454, Solexa 和SOLiD 为代表的第二代高通量测序技术, 以HeliScope TIRM …

MicroRNAs (miRNAs) are a class of small, endogenous RNAs of 21–25 nucleotides (nts) in
length. They play an important regulatory role in animals and plants by targeting specific …

Three subfamilies of grasses, the Ehrhartoideae, Panicoideae and Pooideae, provide the
bulk of human nutrition and are poised to become major sources of renewable energy. Here …

Small RNAs of 20–30 nucleotides can target both chromatin and transcripts, and thereby
keep both the genome and the transcriptome under extensive surveillance. Recent progress …

转录组是特定组织或细胞在某一发育阶段或功能状态下转录出来的所有RNA 的集合.
转录组研究能够从整体水平研究基因功能以及基因结构, 揭示特定生物学过程以及疾病发生过程 …

The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a
protein, but this does not mean that such RNAs do not contain information nor have function …

MicroRNAs (miRNAs) are small, endogenous RNAs that regulate gene expression in plants
and animals. In plants, these∼ 21-nucleotide RNAs are processed from stem-loop regions …

Deciphering the multiple layers of epigenetic regulation that control transcription is critical to
understanding how plants develop and respond to their environment. Using sequencing-by …