Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …

Proton magnetic resonance spectroscopy (1H-MRS) offers a growing variety of methods for
querying potential diagnostic biomarkers of multiple sclerosis in living central nervous …

Objective Prominent inflammation with formation of ectopic B‐cell follicle‐like structures in
the meninges in secondary progressive multiple sclerosis (MS)(SPMS) is associated with …

Objective: The impact of present disease‐modifying treatments (DMTs) in multiple sclerosis
(MS) on nerve injury and reactive astrogliosis is still unclear. Therefore, we studied the effect …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease that
manifests as acute relapses and progressive disability. As a primary endpoint for clinical …

Glucocorticoids (GC) are known for their potent immunosuppressive and anti-inflammatory
properties. As a consequence, they have been extensively used for the treatment of many …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease associated with
axonal injury, and neurofilament light chains in serum (sNfL) are considered a biomarker for …

Introduction The objective of this work is to study the relationship between the presence of
lipid-specific oligoclonal IgM bands (LS-OCMB) in CSF, with both T2 lesion volume (T2LV) …

Axonal degeneration is a major determinant of permanent neurological impairment during
multiple sclerosis (MS). Due to the variable course of clinical disease and the heterogeneity …

Introduction Vitamin D has long been known for its immune-modulating effects, next to its
function in calcium metabolism. As a consequence, poor vitamin D status has been …