Carbohydrate-active enzymes (CAZymes) in the gut microbiome
JF Wardman, RK Bains, P Rahfeld… - Nature Reviews …, 2022 - nature.com
The 1013–1014 microorganisms present in the human gut (collectively known as the human
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …
[HTML][HTML] Amino assets: how amino acids support immunity
Amino acids are fundamental building blocks supporting life. Their role in protein synthesis
is well defined, but they contribute to a host of other intracellular metabolic pathways …
is well defined, but they contribute to a host of other intracellular metabolic pathways …
[HTML][HTML] Structural and mechanistic insights into fungal β-1, 3-glucan synthase FKS1
X Hu, P Yang, C Chai, J Liu, H Sun, Y Wu, M Zhang… - Nature, 2023 - nature.com
The membrane-integrated synthase FKS is involved in the biosynthesis of β-1, 3-glucan, the
core component of the fungal cell wall,. FKS is the target of widely prescribed antifungal …
core component of the fungal cell wall,. FKS is the target of widely prescribed antifungal …
[HTML][HTML] A review of the molecular mechanisms of acaricide resistance in mites and ticks
Abstract The Arachnida subclass of Acari comprises many harmful pests that threaten
agriculture as well as animal health, including herbivorous spider mites, the bee parasite …
agriculture as well as animal health, including herbivorous spider mites, the bee parasite …
[HTML][HTML] Insights into the role of sialylation in cancer progression and metastasis
C Dobie, D Skropeta - British Journal of Cancer, 2021 - nature.com
Upregulation of sialyltransferases—the enzymes responsible for the addition of sialic acid to
growing glycoconjugate chains—and the resultant hypersialylation of up to 40–60% of …
growing glycoconjugate chains—and the resultant hypersialylation of up to 40–60% of …
[HTML][HTML] Structural basis for directional chitin biosynthesis
W Chen, P Cao, Y Liu, A Yu, D Wang, L Chen… - Nature, 2022 - nature.com
Chitin, the most abundant aminopolysaccharide in nature, is an extracellular polymer
consisting of N-acetylglucosamine (GlcNAc) units. The key reactions of chitin biosynthesis …
consisting of N-acetylglucosamine (GlcNAc) units. The key reactions of chitin biosynthesis …
Assembly of bacterial capsular polysaccharides and exopolysaccharides
C Whitfield, SS Wear, C Sande - Annual Review of Microbiology, 2020 - annualreviews.org
Polysaccharides are dominant features of most bacterial surfaces and are displayed in
different formats. Many bacteria produce abundant long-chain capsular polysaccharides …
different formats. Many bacteria produce abundant long-chain capsular polysaccharides …
Catalytic approaches to chemo-and site-selective transformation of carbohydrates
K Yamatsugu, M Kanai - Chemical Reviews, 2023 - ACS Publications
Carbohydrates are a fundamental unit playing pivotal roles in all the biological processes. It
is thus essential to develop methods for synthesizing, functionalizing, and manipulating …
is thus essential to develop methods for synthesizing, functionalizing, and manipulating …
Lignocellulose degradation: An overview of fungi and fungal enzymes involved in lignocellulose degradation
M Andlar, T Rezić, N Marđetko… - Engineering in life …, 2018 - Wiley Online Library
This review aims to present current knowledge of the fungi involved in lignocellulose
degradation with an overview of the various classes of lignocellulose‐acting enzymes …
degradation with an overview of the various classes of lignocellulose‐acting enzymes …
Structure, substrate recognition and initiation of hyaluronan synthase
FP Maloney, J Kuklewicz, RA Corey, Y Bi, R Ho… - Nature, 2022 - nature.com
Hyaluronan is an acidic heteropolysaccharide comprising alternating N-acetylglucosamine
and glucuronic acid sugars that is ubiquitously expressed in the vertebrate extracellular …
and glucuronic acid sugars that is ubiquitously expressed in the vertebrate extracellular …