What we eat, when and how much, all are influenced by brain reward mechanisms that
generate “liking” and “wanting” for foods. As a corollary, dysfunction in reward circuits might …

What brain reward systems mediate motivational 'wanting'and hedonic 'liking'for food
rewards? And what roles do those systems play in eating disorders? This article surveys …

During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has
been used for thousands of years for both recreational and medicinal purposes. In the past …

Marijuana and its major psychotropic component, Δ9-tetrahydrocannabinol, stimulate
appetite and increase body weight in wasting syndromes, suggesting that the CB1 …

Cannabinoid drugs such as Δ 9-THC are euphoric and rewarding, and also stimulate food
intake in humans and animals. Little is known about how naturally occurring endogenous …

Cues associated with tasty foods, such as their smell or taste, are strong motivators of eating,
but the power of food cues on behaviour varies from moment to moment and from person to …

2-Arachidonoylglycerol (2-AG) is a unique molecular species of monoacylglycerol isolated
in 1995 from rat brain and canine gut as an endogenous ligand for the cannabinoid …

There are at least two types of cannabinoid receptor, CB1 and CB2, both G protein coupled.
CB1 receptors are expressed predominantly at nerve terminals and mediate inhibition of …

To date, N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol are the
best studied endocannabinoids and are thought to act as retrograde messengers in the …