A review of UMAP in population genetics
A Diaz-Papkovich, L Anderson-Trocmé… - Journal of Human …, 2021 - nature.com
Uniform manifold approximation and projection (UMAP) has been rapidly adopted by the
population genetics community to study population structure. It has become common in …
population genetics community to study population structure. It has become common in …
Polygenic scores in developmental psychology: Invite genetics in, leave biodeterminism behind
L Raffington, T Mallard… - Annual Review of …, 2020 - annualreviews.org
Polygenic scores offer developmental psychologists new methods for integrating genetic
information into research on how people change and develop across the life span. Indeed …
information into research on how people change and develop across the life span. Indeed …
Genotyping array design and data quality control in the Million Veteran Program
The Million Veteran Program (MVP), initiated by the Department of Veterans Affairs (VA),
aims to collect biosamples with consent from at least one million veterans. Presently, blood …
aims to collect biosamples with consent from at least one million veterans. Presently, blood …
Cultural evolution of genetic heritability
R Uchiyama, R Spicer… - Behavioral and Brain …, 2022 - cambridge.org
Behavioral genetics and cultural evolution have both revolutionized our understanding of
human behavior–largely independent of each other. Here, we reconcile these two fields …
human behavior–largely independent of each other. Here, we reconcile these two fields …
Revealing the recent demographic history of Europe via haplotype sharing in the UK Biobank
E Gilbert, A Shanmugam… - Proceedings of the …, 2022 - National Acad Sciences
Haplotype-based analyses have recently been leveraged to interrogate the fine-scale
structure in specific geographic regions, notably in Europe, although an equivalent …
structure in specific geographic regions, notably in Europe, although an equivalent …
Relative impact of genetic ancestry and neighborhood socioeconomic status on all-cause mortality in self-identified African Americans
Self-identified race/ethnicity is a correlate of both genetic ancestry and socioeconomic
factors, both of which may contribute to racial disparities in mortality. Investigators often hold …
factors, both of which may contribute to racial disparities in mortality. Investigators often hold …
A genomic data archive from the Network for Pancreatic Organ donors with Diabetes
DJ Perry, MR Shapiro, SW Chamberlain, I Kusmartseva… - Scientific data, 2023 - nature.com
Abstract The Network for Pancreatic Organ donors with Diabetes (nPOD) is the largest
biorepository of human pancreata and associated immune organs from donors with type 1 …
biorepository of human pancreata and associated immune organs from donors with type 1 …
Leveraging genetic ancestry to study health disparities
K Batai, S Hooker, RA Kittles - American Journal of Physical …, 2021 - Wiley Online Library
Research to understand human genomic variation and its implications in health has great
potential to contribute in the reduction of health disparities. Biological anthropology can play …
potential to contribute in the reduction of health disparities. Biological anthropology can play …
Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region
An individual's disease risk is affected by the populations that they belong to, due to shared
genetics and environmental factors. The study of fine-scale populations in clinical care is …
genetics and environmental factors. The study of fine-scale populations in clinical care is …
Uncovering signals of positive selection in Peruvian populations from three ecological regions
R Caro-Consuegra, MA Nieves-Colón… - Molecular biology …, 2022 - academic.oup.com
Peru hosts extremely diverse ecosystems which can be broadly classified into the following
three major ecoregions: the Pacific desert coast, the Andean highlands, and the Amazon …
three major ecoregions: the Pacific desert coast, the Andean highlands, and the Amazon …