A review of UMAP in population genetics

A Diaz-Papkovich, L Anderson-Trocmé… - Journal of Human …, 2021 - nature.com
Uniform manifold approximation and projection (UMAP) has been rapidly adopted by the
population genetics community to study population structure. It has become common in …

Polygenic scores in developmental psychology: Invite genetics in, leave biodeterminism behind

L Raffington, T Mallard… - Annual Review of …, 2020 - annualreviews.org
Polygenic scores offer developmental psychologists new methods for integrating genetic
information into research on how people change and develop across the life span. Indeed …

Genotyping array design and data quality control in the Million Veteran Program

H Hunter-Zinck, Y Shi, M Li, BR Gorman, SG Ji… - The American Journal of …, 2020 - cell.com
The Million Veteran Program (MVP), initiated by the Department of Veterans Affairs (VA),
aims to collect biosamples with consent from at least one million veterans. Presently, blood …

Cultural evolution of genetic heritability

R Uchiyama, R Spicer… - Behavioral and Brain …, 2022 - cambridge.org
Behavioral genetics and cultural evolution have both revolutionized our understanding of
human behavior–largely independent of each other. Here, we reconcile these two fields …

Revealing the recent demographic history of Europe via haplotype sharing in the UK Biobank

E Gilbert, A Shanmugam… - Proceedings of the …, 2022 - National Acad Sciences
Haplotype-based analyses have recently been leveraged to interrogate the fine-scale
structure in specific geographic regions, notably in Europe, although an equivalent …

Relative impact of genetic ancestry and neighborhood socioeconomic status on all-cause mortality in self-identified African Americans

HS Iyer, SL Gomez, I Cheng, TR Rebbeck - PLoS One, 2022 - journals.plos.org
Self-identified race/ethnicity is a correlate of both genetic ancestry and socioeconomic
factors, both of which may contribute to racial disparities in mortality. Investigators often hold …

A genomic data archive from the Network for Pancreatic Organ donors with Diabetes

DJ Perry, MR Shapiro, SW Chamberlain, I Kusmartseva… - Scientific data, 2023 - nature.com
Abstract The Network for Pancreatic Organ donors with Diabetes (nPOD) is the largest
biorepository of human pancreata and associated immune organs from donors with type 1 …

Leveraging genetic ancestry to study health disparities

K Batai, S Hooker, RA Kittles - American Journal of Physical …, 2021 - Wiley Online Library
Research to understand human genomic variation and its implications in health has great
potential to contribute in the reduction of health disparities. Biological anthropology can play …

Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region

C Caggiano, A Boudaie, R Shemirani, J Mefford… - Nature Medicine, 2023 - nature.com
An individual's disease risk is affected by the populations that they belong to, due to shared
genetics and environmental factors. The study of fine-scale populations in clinical care is …

Uncovering signals of positive selection in Peruvian populations from three ecological regions

R Caro-Consuegra, MA Nieves-Colón… - Molecular biology …, 2022 - academic.oup.com
Peru hosts extremely diverse ecosystems which can be broadly classified into the following
three major ecoregions: the Pacific desert coast, the Andean highlands, and the Amazon …