[HTML][HTML] Molecular insight into pentraxin-3: Update advances in innate immunity, inflammation, tissue remodeling, diseases, and drug role

H Zhang, R Wang, Z Wang, W Wu, N Zhang… - Biomedicine & …, 2022 - Elsevier
Abstract Pentraxin-3 (PTX3) is the prototype of the long pentraxin subfamily, an acute-phase
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …

MicroRNAs and periodontal homeostasis

X Luan, X Zhou, J Trombetta-eSilva… - Journal of dental …, 2017 - journals.sagepub.com
MicroRNAs (miRNAs) are a group of small RNAs that control gene expression in all aspects
of eukaryotic life, primarily through RNA silencing mechanisms. The purpose of the present …

SOXC are critical regulators of adult bone mass

M Angelozzi, A Karvande, V Lefebvre - Nature Communications, 2024 - nature.com
Pivotal in many ways for human health, the control of adult bone mass is governed by
complex, incompletely understood crosstalk namely between mesenchymal stem cells …

Emerging prognostic markers related to mesenchymal characteristics of poorly differentiated breast cancers

M Scimeca, C Antonacci, D Colombo, R Bonfiglio… - Tumor Biology, 2016 - Springer
Despite the screening program, breast cancer is the commonest cause of cancer death in
women in the industrialized world. In this study, we investigate the correlation among poorly …

Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants

BM de Sousa, CR Correia, JAF Ferreira… - NPJ Regenerative …, 2021 - nature.com
Replacement orthopedic surgeries are among the most common surgeries worldwide, but
clinically used passive implants cannot prevent failure rates and inherent revision …

Radiological, histological and chemical analysis of breast microcalcifications: diagnostic value and biological significance

R Bonfiglio, M Scimeca, N Toschi, CA Pistolese… - Journal of mammary …, 2018 - Springer
Classification of mammary microcalcifications is based on radiological and histological
characteristics that are routinely evaluated during the diagnostic path for the identification of …

Effect of inflammation on bones in diabetic patients with periodontitis via RANKL/OPG system-A review

H Ateeq, A Zia, Q Husain, MS Khan… - Journal of Diabetes & …, 2022 - Springer
Purpose Diabetes mellitus and periodontitis are inflammatory diseases, the severity of
inflammation results in the progression and persistence of both the disorders and affects …

Impairment of PTX3 expression in osteoblasts: a key element for osteoporosis

M Scimeca, A Salustri, E Bonanno, D Nardozi… - Cell death & …, 2017 - nature.com
Abstract Pentraxin 3 (PTX3) is a multifunctional glycoprotein regulating inflammatory
response, cell proliferation and migration and deposition and remodelling of the …

The long pentraxin 3 plays a role in bone turnover and repair

D Grčević, M Sironi, S Valentino, L Deban… - Frontiers in …, 2018 - frontiersin.org
Pentraxin 3 (PTX3) is an inflammatory mediator acting as a fluid-phase pattern recognition
molecule and playing an essential role in innate immunity and matrix remodeling …

The long pentraxin PTX3 in bone homeostasis and pathology

R Parente, C Sobacchi, B Bottazzi… - Frontiers in …, 2019 - frontiersin.org
The innate immune system is equipped with a number of germ-line encoded soluble pattern
recognition molecules (PRMs) that collectively mediate the humoral host response to …