Mechanobiology of the brain in ageing and Alzheimer's disease
CM Hall, E Moeendarbary… - European Journal of …, 2021 - Wiley Online Library
Just as the epigenome, the proteome and the electrophysiological properties of a cell
influence its function, so too do its intrinsic mechanical properties and its extrinsic …
influence its function, so too do its intrinsic mechanical properties and its extrinsic …
Hippo signaling pathway and respiratory diseases
W Tang, M Li, X Yangzhong, X Zhang, A Zu… - Cell Death …, 2022 - nature.com
The hippo signaling pathway is a highly conserved evolutionary signaling pathway that
plays an important role in regulating cell proliferation, organ size, tissue development, and …
plays an important role in regulating cell proliferation, organ size, tissue development, and …
The Hippo signaling pathway in development and regeneration
The Hippo signaling pathway is a central growth control mechanism in multicellular
organisms. By integrating diverse mechanical, biochemical, and stress cues, the Hippo …
organisms. By integrating diverse mechanical, biochemical, and stress cues, the Hippo …
[HTML][HTML] An update on the role of Hippo signaling pathway in ischemia-associated central nervous system diseases
X Wei, G Huang, J Liu, J Ge, W Zhang, Z Mei - Biomedicine & …, 2023 - Elsevier
The most frequent reason of morbidity and mortality in the world, cerebral ischemia sets off a
chain of molecular and cellular pathologies that associated with some central nervous …
chain of molecular and cellular pathologies that associated with some central nervous …
Recent advances of the Hippo/YAP signaling pathway in brain development and glioma
T Ouyang, W Meng, M Li, T Hong, N Zhang - Cellular and molecular …, 2020 - Springer
The Hippo signaling pathway is highly conserved from Drosophila melanogaster to
mammals and plays a crucial role in organ size control, tissue regeneration, and tumor …
mammals and plays a crucial role in organ size control, tissue regeneration, and tumor …
Neuronal Hippo signaling: From development to diseases
Hippo signaling pathway is a highly conserved and familiar tissue growth regulator, primarily
dealing with cell survival, cell proliferation, and apoptosis. The Yes‐associated protein …
dealing with cell survival, cell proliferation, and apoptosis. The Yes‐associated protein …
Increased susceptibility to cerebral microhemorrhages is associated with imaging signs of microvascular degeneration in the retina in an insulin-like growth factor 1 …
LR Miller, S Tarantini, Á Nyúl-Tóth… - Frontiers in Aging …, 2022 - frontiersin.org
Age-related cerebrovascular defects contribute to vascular cognitive impairment and
dementia (VCID) as well as other forms of dementia. There has been great interest in …
dementia (VCID) as well as other forms of dementia. There has been great interest in …
A non-canonical Hedgehog pathway initiates ciliogenesis and autophagy
T Akhshi, WS Trimble - Journal of Cell Biology, 2020 - rupress.org
Primary cilia function as critical signaling hubs whose absence leads to severe disorders
collectively known as ciliopathies; our knowledge of ciliogenesis remains limited. We show …
collectively known as ciliopathies; our knowledge of ciliogenesis remains limited. We show …
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT
WWC1 regulates episodic learning and memory, and genetic nucleotide polymorphism of
WWC1 is associated with neurodegenerative diseases such as Alzheimer's disease …
WWC1 is associated with neurodegenerative diseases such as Alzheimer's disease …
The Amot/integrin protein complex transmits mechanical forces required for vascular expansion
Y Zhang, Y Zhang, S Kameishi, G Barutello, Y Zheng… - Cell reports, 2021 - cell.com
Vascular development is a complex multistep process involving the coordination of cellular
functions such as migration, proliferation, and differentiation. How mechanical forces …
functions such as migration, proliferation, and differentiation. How mechanical forces …