Review on metal nanoparticles as nanocarriers: Current challenges and perspectives in drug delivery systems

V Chandrakala, V Aruna, G Angajala - Emergent Materials, 2022 - Springer
Over the past few years, nanotechnology has been attracting considerable research
attention because of their outstanding mechanical, electromagnetic and optical properties …

A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery

U Anand, N Jacobo-Herrera, A Altemimi, N Lakhssassi - Metabolites, 2019 - mdpi.com
The war on multidrug resistance (MDR) has resulted in the greatest loss to the world's
economy. Antibiotics, the bedrock, and wonder drug of the 20th century have played a …

Modeling the expansion of virtual screening libraries

J Lyu, JJ Irwin, BK Shoichet - Nature chemical biology, 2023 - nature.com
Recently,'tangible'virtual libraries have made billions of molecules readily available.
Prioritizing these molecules for synthesis and testing demands computational approaches …

Concepts of artificial intelligence for computer-assisted drug discovery

X Yang, Y Wang, R Byrne, G Schneider… - Chemical …, 2019 - ACS Publications
Artificial intelligence (AI), and, in particular, deep learning as a subcategory of AI, provides
opportunities for the discovery and development of innovative drugs. Various machine …

Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy

S Hossain, Z Urbi, H Karuniawati, RB Mohiuddin… - Life, 2021 - mdpi.com
Infectious disease (ID) is one of the top-most serious threats to human health globally,
further aggravated by antimicrobial resistance and lack of novel immunization options …

Nano based drug delivery systems: recent developments and future prospects

JK Patra, G Das, LF Fraceto, EVR Campos… - Journal of …, 2018 - Springer
Nanomedicine and nano delivery systems are a relatively new but rapidly developing
science where materials in the nanoscale range are employed to serve as means of …

Mining genomes to illuminate the specialized chemistry of life

MH Medema, T de Rond, BS Moore - Nature Reviews Genetics, 2021 - nature.com
All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …

Natural products for drug discovery in the 21st century: innovations for novel drug discovery

NE Thomford, DA Senthebane, A Rowe… - International journal of …, 2018 - mdpi.com
The therapeutic properties of plants have been recognised since time immemorial. Many
pathological conditions have been treated using plant-derived medicines. These medicines …

Natural product drug discovery in the artificial intelligence era

FI Saldívar-González, VD Aldas-Bulos… - Chemical …, 2022 - pubs.rsc.org
Natural products (NPs) are primarily recognized as privileged structures to interact with
protein drug targets. Their unique characteristics and structural diversity continue to marvel …

Improving curcumin bioavailability: Current strategies and future perspectives

R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …