Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Naphthoquinones are compounds present in several families of higher plants. Their
molecular structures confer redox properties, and they are involved in multiple biological …

Background Leishmaniasis, a parasitic disease caused by protozoa of the genus
Leishmania, affects more than 12 million people worldwide. Quercetin has generated …

Mitochondrial reactive oxygen species (mROS) have been considered detrimental to cells.
However, their physiological roles as signaling mediators have not been thoroughly …

To discover new possible therapies for Chagas' disease, we evaluated against all
Trypanosoma cruzi life stages the in vitro trypanocidal and synergistic activity of terpenes …

Trypanosoma cruzi, the causative agent of Chagas disease, is an obligatory intracellular
parasite with a digenetic life cycle. Due to the variety of host environments, it faces several …

Chagas disease is one of the most important endemic diseases in Latin America, caused by
Trypanosoma cruzi. The drugs used for the treatment of this disease, nifurtimox and …

Cervical cancer is a health problem among women worldwide. Considering the limitations of
prevention and antineoplastic chemotherapy against cervical cancer, research is needed to …

Leishmaniasis is an important neglected disease caused by protozoa of the genus
Leishmania that affects more than 12 million people worldwide. Leishmaniasis treatment …

In the past decade, scientific advances in network pharmacology have laid the foundations
for a polypharmacological approach to discover new drugs for complex diseases. There is …