Fungal infections are rising, with over 1.5 billion cases and more than 1 million deaths
recorded each year. Among these, Candida infections are frequent in at-risk populations …

Fungal pathogens cause over 6.5 million life-threatening systemic infections annually, with
mortality rates ranging from 20 to 95%, even with medical intervention. The World Health …

Candida albicans is a commensal yeast of the human intestinal microbiota that, under
predisposing conditions, can become pathogenic and cause life-threatening systemic …

Fungal pathogens are increasingly appreciated as a significant infectious disease
challenge. Compared to bacteria, fungal cells are more closely related to human cells, and …

Antifungal resistance and antifungal tolerance are two distinct terms that describe different
cellular responses to drugs. Antifungal resistance describes the ability of a fungus to grow …

Fungal infections are increasing globally, causing alarmingly high mortality and economic
burden. In addition to antifungal resistance, other more subtle drug responses appear to …

Candida auris is an emerging fungal pathogen with several concerning qualities. First
recognized in 2009, it has arisen in multiple geographically distinct genomic clades nearly …

Heteroresistance to antifungal agents poses a significant challenge in the treatment of
fungal infections. Currently, the absence of established methods for detecting and …

Infections caused by Candida spp. pose a continuing challenge for modern medicine, due to
widespread resistance to commonly used antifungal agents (eg, azoles). Thus, there is …

The study of pathogenicity and virulence of fungal strains, in vivo in the preclinical phase, is
carried out through the use of animal models belonging to various classes of mammals …