Possible neuroprotective mechanisms of physical exercise in neurodegeneration

B Mahalakshmi, N Maurya, SD Lee… - International journal of …, 2020 - mdpi.com
Physical exercise (PE) improves physical performance, mental status, general health, and
well-being. It does so by affecting many mechanisms at the cellular and molecular level. PE …

The neuroprotective effects of exercise: maintaining a healthy brain throughout aging

LM Vecchio, Y Meng, K Xhima, N Lipsman… - Brain …, 2018 - content.iospress.com
Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Exercise benefits brain function: the monoamine connection

TW Lin, YM Kuo - Brain sciences, 2013 - mdpi.com
The beneficial effects of exercise on brain function have been demonstrated in animal
models and in a growing number of clinical studies on humans. There are multiple …

[HTML][HTML] Physical exercise-induced fatigue: the role of serotonergic and dopaminergic systems

LMS Cordeiro, PCR Rabelo, MM Moraes… - Brazilian journal of …, 2017 - SciELO Brasil
Brain serotonin and dopamine are neurotransmitters related to fatigue, a feeling that leads to
reduced intensity or interruption of physical exercises, thereby regulating performance. The …

Pharmacogenetics and the serotonin system: initial studies and future directions

J Veenstra-VanderWeele, GM Anderson… - European journal of …, 2000 - Elsevier
Serotonin (5-hydroxytryptamine, 5-HT) appears to play a role in the pathophysiology of a
range of neuropsychiatric disorders, and serotonergic agents are of central importance in …

Regular voluntary exercise reduces anxiety-related behaviour and impulsiveness in mice

E Binder, SK Droste, F Ohl, JMHM Reul - Behavioural brain research, 2004 - Elsevier
We embarked on a study to delineate the behavioural changes in mice after 4 weeks of
voluntary exercise. As an initial behavioural characterization, we exposed the control and …

The effects of different aerobic exercise intensities on serum serotonin concentrations and their association with Stroop task performance: a randomized controlled trial

P Zimmer, C Stritt, W Bloch, FP Schmidt… - European journal of …, 2016 - Springer
Purpose Acute exercise improves selective aspects of cognition such as executive
functioning. Animal studies suggest that some effects are based on exercise-induced …

Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha1b-adrenergic receptor mRNA in the rat raphe nuclei

BN Greenwood, TE Foley, HEW Day, D Burhans… - Biological …, 2005 - Elsevier
BACKGROUND: Altered serotonergic (5-HT) neurotransmission is implicated in the
antidepressant and anxiolytic properties of physical activity. In the current study, we …

Complicated role of exercise in modulating memory: a discussion of the mechanisms involved

M Ebrahimnejad, P Azizi, V Alipour… - Neurochemical …, 2022 - Springer
Evidence has shown the beneficial effects of exercise on learning and memory. However,
many studies have reported controversial results, indicating that exercise can impair …

[HTML][HTML] Interactions between genetic risk for 21 neurodevelopmental and psychiatric disorders and sport activity on youth mental health

MC Misztal, ES Tio, A Mohan, D Felsky - Psychiatry research, 2023 - Elsevier
Childhood is a sensitive period where behavioral disturbances, determined by genetics and
environmental factors including sport activity, may emerge and impact risk of mental illness …