Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

Diabetic kidney disease (DKD) is one of the main causes of end-stage renal disease
(ESRD) and all-cause mortality in diabetic patients, despite the extensive use of angiotensin …

Aim Cyclophosphamide (CP) is used to treat a variety of cancers and autoimmune illnesses.
CP has been found to frequently cause premature ovarian failure (POF). The study's …

Doxorubicin (DOX)-based chemotherapy induces cardiotoxicity, which is considered the
main bottleneck for its clinical application. In this study, we investigated the potential benefit …

The pathogenesis of diabetic nephropathy (DN) involves cellular activation of oxidative
stress and inflammation. Eriodictyol is a citrus-derived flavonoid with multiple …

LCZ696 (valsartan/sacubitril) has the potential to slow the progression of diabetic kidney
disease (DKD) according to previous reports. However, the renoprotective mechanism …

The angiotensin receptor neprilysin inhibitor LCZ696 affords superior cardioprotection and
renoprotection compared with renin-angiotensin blockade monotherapy, but the underlying …

Background Cyclophosphamide (CP) is a widely used chemotherapeutic drug. However, the
associated nephrotoxicity restricts its clinical use. Aim The present research was designed to …

Although renin-angiotensin blockade has shown beneficial outcomes in patients with
diabetes, renal injury progresses in most of these patients. Therefore, there remains a need …

Traumatic brain injury (TBI) is among the most debilitating neurological disorders with
inadequate therapeutic options. It affects all age groups globally leading to post‐TBI …