Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
Adverse events in clinical treatments with serotonergic psychedelics and MDMA: A mixed-methods systematic review
JJ Breeksema, BW Kuin, J Kamphuis… - Journal of …, 2022 - journals.sagepub.com
Introduction: Small-scale clinical studies with psychedelic drugs have shown promising
results for the treatment of several mental disorders. Before psychedelics become registered …
results for the treatment of several mental disorders. Before psychedelics become registered …
MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled …
MC Mithoefer, AA Feduccia, L Jerome, A Mithoefer… - …, 2019 - Springer
Background Posttraumatic stress disorder is a prevalent mental health condition with
substantial impact on daily functioning that lacks sufficient treatment options. Here we …
substantial impact on daily functioning that lacks sufficient treatment options. Here we …
Reviewing the potential of psychedelics for the treatment of PTSD
E Krediet, T Bostoen, J Breeksema… - International Journal …, 2020 - academic.oup.com
There are few medications with demonstrated efficacy for the treatment of posttraumatic
stress disorder (PTSD). Treatment guidelines have unequivocally designated psychotherapy …
stress disorder (PTSD). Treatment guidelines have unequivocally designated psychotherapy …
Sex/gender differences in the time-course for the development of substance use disorder: a focus on the telescoping effect
EB Towers, IL Williams, EI Qillawala, EF Rissman… - Pharmacological …, 2023 - ASPET
Sex/gender effects have been demonstrated for multiple aspects of addiction, with one of the
most commonly cited examples being the “telescoping effect” where women meet criteria …
most commonly cited examples being the “telescoping effect” where women meet criteria …
Acute effects of lysergic acid diethylamide in healthy subjects
Y Schmid, F Enzler, P Gasser, E Grouzmann… - Biological …, 2015 - Elsevier
Background After no research in humans for> 40 years, there is renewed interest in using
lysergic acid diethylamide (LSD) in clinical psychiatric research and practice. There are no …
lysergic acid diethylamide (LSD) in clinical psychiatric research and practice. There are no …
Breakthrough for trauma treatment: safety and efficacy of MDMA-assisted psychotherapy compared to paroxetine and sertraline
AA Feduccia, L Jerome, B Yazar-Klosinski… - Frontiers in …, 2019 - frontiersin.org
Unsuccessfully treated posttraumatic stress disorder (PTSD) is a serious and life-threatening
disorder. Two medications, paroxetine hydrochloride and sertraline hydrochloride, are …
disorder. Two medications, paroxetine hydrochloride and sertraline hydrochloride, are …
Pharmacological characterization of designer cathinones in vitro
LD Simmler, TA Buser, M Donzelli… - British journal of …, 2013 - Wiley Online Library
Background and Purpose Designer β‐keto amphetamines (eg cathinones,'bath salts' and
'research chemicals') have become popular recreational drugs, but their pharmacology is …
'research chemicals') have become popular recreational drugs, but their pharmacology is …
The safety and efficacy of±3, 4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder …
MC Mithoefer, MT Wagner… - Journal of …, 2011 - journals.sagepub.com
Case reports indicate that psychiatrists administered±3, 4-
methylenedioxymethamphetamine (MDMA) as a catalyst to psychotherapy before …
methylenedioxymethamphetamine (MDMA) as a catalyst to psychotherapy before …
Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3, 4-methylenedioxymethamphetamine …
MC Mithoefer, MT Wagner… - Journal of …, 2013 - journals.sagepub.com
We report follow-up data evaluating the long-term outcomes for the first completed trial of 3,
4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for chronic, treatment …
4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for chronic, treatment …