Improving through-plane thermal conductivity of PDMS-based composites using highly oriented carbon fibers bridged by Al2O3 particles

R Huang, D Ding, X Guo, C Liu, X Li, G Jiang… - … Science and Technology, 2022 - Elsevier
Efficient thermal interface materials (TIMs) are urgently needed for heat dissipation of high-
power density electronics. In this study, vinyl polydimethylsiloxane (PDMS) composites with …

The impact of serum-free culture on HEK293 cells: From the establishment of suspension and adherent serum-free adaptation cultures to the investigation of growth …

M Jang, ES Pete, P Bruheim - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Serum-free cultures are preferred for application in clinical cell therapy and facilitate the
purification processes of bioproducts, such as vaccines and recombinant proteins. It can …

AAV process intensification by perfusion bioreaction and integrated clarification

JP Mendes, B Fernandes, E Pineda… - … in Bioengineering and …, 2022 - frontiersin.org
Adeno-associated viruses (AAVs) demand for clinical trials and approved therapeutic
applications is increasing due to this vector's overall success and potential. The high doses …

Improvement of HEK293 cell growth by adapting hydrodynamic stress and predicting cell aggregate size distribution

S Seidel, RW Maschke, F Mozaffari, R Eibl-Schindler… - Bioengineering, 2023 - mdpi.com
HEK293 is a widely used cell line in the fields of research and industry. It is assumed that
these cells are sensitive to hydrodynamic stress. The aim of this research was to use particle …

An endothelial cell is not simply an endothelial cell

S Limbu, KE McCloskey - Stem Cells and Development, 2024 - liebertpub.com
Endothelial cells (ECs) are a multifaceted component of the vascular system with roles in
immunity, maintaining tissue fluid balance, and vascular tone. Dysregulation or dysfunction …

[PDF][PDF] Isolation, Antibacterial Characterization, and ATF-Based Preparation of Viable Cells of Lacticaseibacillus paracasei XLK 401 and Its Potential Application in Milk …

WG Xin, XD Li, HY Zhou, X Li, WX Liu, LB Lin… - J. Dairy …, 2023 - scholar.archive.org
It is desirable to obtain high levels of viable Lacticaseibacillus paracasei, a widely used food
probiotic whose antibacterial activity and potential application in milk remain largely …

Scaling strategy for cell and gene therapy bioreactors based on turbulent parameters

D Iurashev, PA Jones, N Andreev, Y Wang… - Biotechnology …, 2024 - Wiley Online Library
So far, power input has been used as the main parameter for bioreactor scale‐up/‐down in
upstream process development and manufacturing. The rationale is that maintaining a …

[HTML][HTML] Suppressors of amyloid-β toxicity improve recombinant protein production in yeast by reducing oxidative stress and tuning cellular metabolism

X Chen, X Li, B Ji, Y Wang, OP Ishchuk… - Metabolic …, 2022 - Elsevier
High-level production of recombinant proteins in industrial microorganisms is often limited
by the formation of misfolded proteins or protein aggregates, which consequently induce …

Intensified and continuous mAb production with single-use systems

J Müller, M Teale, S Steiner, S Junne… - Cell Culture Engineering …, 2022 - Springer
Therapeutic monoclonal antibodies (mAbs) are the fastest-growing class of biotherapeutics.
They are mainly used to treat cancer, inflammatory, metabolic and autoimmune diseases …

Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtration

S Göbel, L Pelz, CAT Silva, B Brühlmann, C Hill… - Applied Microbiology …, 2024 - Springer
Cell culture-based production of vector-based vaccines and virotherapeutics is of increasing
interest. The vectors used not only retain their ability to infect cells but also induce robust …