Carbon nanotubes in biomedical applications: factors, mechanisms, and remedies of toxicity: miniperspective

R Alshehri, AM Ilyas, A Hasan, A Arnaout… - Journal of medicinal …, 2016 - ACS Publications
Carbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The
unique physicochemical properties of CNTs make them among prime candidates for …

Future of nanotherapeutics: Targeting the cellular sub-organelles

X Ma, N Gong, L Zhong, J Sun, XJ Liang - Biomaterials, 2016 - Elsevier
Many diseases originate from alterations at nanoscale levels. Precise drug delivery should
be achieved not only at cell level, but also at organelle level to achieve maximum …

Polymer-coated carbon nanotube hybrids with functional peptides for gene delivery into plant mitochondria

SSY Law, G Liou, Y Nagai, J Giménez-Dejoz… - Nature …, 2022 - nature.com
The delivery of genetic material into plants has been historically challenging due to the cell
wall barrier, which blocks the passage of many biomolecules. Carbon nanotube-based …

Recent advances in targeted tumor chemotherapy based on smart nanomedicines

SY Qin, AQ Zhang, XZ Zhang - Small, 2018 - Wiley Online Library
Efficacy and safety of chemotherapeutic drugs constitute two major criteria in tumor
chemotherapy. Nanomedicines with tumor‐targeted properties hold great promise for …

Noncovalent ruthenium (II) complexes–single-walled carbon nanotube composites for bimodal photothermal and photodynamic therapy with near-infrared irradiation

P Zhang, H Huang, J Huang, H Chen… - … applied materials & …, 2015 - ACS Publications
To enhance the efficacy and optimize the treatment of cancers, the integration of multimodal
treatment strategies leading to synergistic effects is a promising approach. The coassembly …

Targeted nanoparticles in mitochondrial medicine

RK Pathak, N Kolishetti, S Dhar - … Reviews: Nanomedicine and …, 2015 - Wiley Online Library
Mitochondria, the so‐called 'energy factory of cells' not only produce energy but also
contribute immensely in cellular mortality management. Mitochondrial dysfunctions result in …

Bio‐Conjugated Advanced Materials for Targeted Disease Theranostics

XL Hu, N Kwon, KC Yan, AC Sedgwick… - Advanced Functional …, 2020 - Wiley Online Library
Human beings are “machines” that use endogenously produced biomolecules as
“components” in signaling and for the maintenance of the body. These biomolecules consist …

Novel strategies for disrupting cancer-cell functions with mitochondria-targeted antitumor drug–loaded nanoformulations

KS Allemailem, A Almatroudi, MA Alsahli… - International Journal …, 2021 - Taylor & Francis
Any variation in normal cellular function results in mitochondrial dysregulation that occurs in
several diseases, including cancer. Such processes as oxidative stress, metabolism …

Nanomedicine in cancer therapy

D Fan, Y Cao, M Cao, Y Wang, Y Cao… - Signal Transduction and …, 2023 - nature.com
Cancer remains a highly lethal disease in the world. Currently, either conventional cancer
therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that …

Mitochondria-targeted hydroxyapatite nanoparticles for selective growth inhibition of lung cancer in vitro and in vivo

Y Sun, Y Chen, X Ma, Y Yuan, C Liu… - ACS Applied Materials …, 2016 - ACS Publications
Lung cancer is the leading cause of cancer-related mortality worldwide. Most patients have
metastases at the time of diagnosis, thus demanding development of more effective and …