Chronic cough is globally prevalent across all age groups. This disorder is challenging to
treat because many pulmonary and extrapulmonary conditions can present with chronic …

Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …

The slogan “Coughs and Sneezes Spread Diseases” was coined in the United States during
the last great flu pandemic between 1918 and 1920 to highlight the role of coughs and …

The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

We present a machine learning based COVID-19 cough classifier which can discriminate
COVID-19 positive coughs from both COVID-19 negative and healthy coughs recorded on a …

Background Preclinical studies suggest that P2X3 receptors are expressed by airway vagal
afferent nerves and contribute to the hypersensitisation of sensory neurons. P2X3 receptors …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

This book presents 55 clinical cases emphasizing the basic science aspects of pathology
and is “the closest you can get to the wards without seeing patients.” Each case includes an …

Background Chronic refractory cough (CRC) is a difficult problem to treat. Speech pathology
treatment (SPT) improves symptoms but resolution is incomplete. Centrally acting …

Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive
myelinated sensory nerves play essential roles in regulating cough. These vagal sensory …