Radical trifluoromethylation - Chemical Society Reviews (RSC Publishing) DOI:10.1039/D1CS00200G
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Fluorinated molecules have a wide range of applications and are used as medicines,
agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar …

Aryl diazonium salts are versatile building blocks in organic synthesis. In light of the ever-
increasing importance of aryl diazonium salts spanning most disciplines of the chemical …

Fluorine has emerged as a “magic element” in medicinal chemistry, crop, and materials
science. 1 Although fluorine is the most abundant halogen in the earth's crust, it is contained …

Fluorine, often called as “a small atom with a big ego”, 1 lies in the second row and the 17th
column in the periodic table of the chemical elements. This unique position in the periodic …

Incorporation of the CF3 group into arenes has found increasing importance in drug
discovery. Herein, we report the first photoredox‐catalyzed cross‐coupling of aryl …

This review provides a brief assessment of the methodological field of trifluoromethylation
and its possible impact on the development of new CF 3-containing pharmaceuticals …

Much progress has been made in the development of methods to both create compounds
that contain C− F bonds and to functionalize C− F bonds. As such, C− F bonds are becoming …

Electrophotochemistry has enabled arene C− H trifluoromethylation with the Langlois
reagent CF3SO2Na under mild reaction conditions. The merger of electrosynthesis and …

The mechanisms of most organic reactions are considered to proceed by two-electron
transfer pathways, even though both biology and radical chemistry rely extensively on one …