Cryoprotectants: A review of the actions and applications of cryoprotective solutes that modulate cell recovery from ultra-low temperatures

GD Elliott, S Wang, BJ Fuller - Cryobiology, 2017 - Elsevier
Cryopreservation has become a central technology in many areas of clinical medicine,
biotechnology, and species conservation within both plant and animal biology …

Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?

M Awan, I Buriak, R Fleck, B Fuller, A Goltsev… - Regenerative …, 2020 - Taylor & Francis
Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since
the early history of cryopreservation. It has been used for decades in many thousands of cell …

The need for novel cryoprotectants and cryopreservation protocols: Insights into the importance of biophysical investigation and cell permeability

R Raju, SJ Bryant, BL Wilkinson, G Bryant - Biochimica et Biophysica Acta …, 2021 - Elsevier
Background Cryopreservation is a key method of preservation of biological material for both
medical treatments and conservation of endangered species. In order to avoid cellular …

Phytochemical Characterization, Antioxidant Activity, and Cytotoxicity of Methanolic Leaf Extract of Chlorophytum Comosum (Green Type) (Thunb.) Jacq

IV Rzhepakovsky, DA Areshidze, SS Avanesyan… - Molecules, 2022 - mdpi.com
Chlorophytum genus has been extensively studied due to its diverse biological activities. We
evaluated the methanolic extract of leaves of Chlorophytum comosum (Green type)(Thunb.) …

Advanced technologies for the preservation of mammalian biospecimens

H Huang, X He, ML Yarmush - Nature biomedical engineering, 2021 - nature.com
The three classical core technologies for the preservation of live mammalian biospecimens—
slow freezing, vitrification and hypothermic storage—limit the biomedical applications of …

Microfluidics for cryopreservation

G Zhao, J Fu - Biotechnology advances, 2017 - Elsevier
Cryopreservation has utility in clinical and scientific research but implementation is highly
complex and includes labor-intensive cell-specific protocols for the addition/removal of …

[HTML][HTML] Silk fibroin/chitosan/alginate multilayer membranes as a system for controlled drug release in wound healing

MS Pacheco, GE Kano, L de Almeida Paulo… - International journal of …, 2020 - Elsevier
In this study, we proposed the use of the biopolymers silk fibroin, chitosan and alginate,
which are recognized for their biocompatibility and biodegradability, for the preparation of …

Cryopreservation of NK and T cells without DMSO for adoptive cell-based immunotherapy

X Yao, S Matosevic - BioDrugs, 2021 - Springer
Dimethylsufoxide (DMSO) being universally used as a cryoprotectant in clinical adoptive cell-
therapy settings to treat hematological malignancies and solid tumors is a growing concern …

Rapid quantification of multi-cryoprotectant toxicity using an automated liquid handling method

RM Warner, E Ampo, D Nelson, JD Benson, A Eroglu… - Cryobiology, 2021 - Elsevier
Cryopreservation in a vitrified state has vast potential for long-term storage of tissues and
organs that may be damaged by ice formation. However, the toxicity imparted by the high …

A toxicity cost function approach to optimal CPA equilibration in tissues

JD Benson, AZ Higgins, K Desai, A Eroglu - Cryobiology, 2018 - Elsevier
There is growing need for cryopreserved tissue samples that can be used in transplantation
and regenerative medicine. While a number of specific tissue types have been successfully …