Expanding the antifungal drug arsenal for treating Candida infections is crucial in this era of
the rising life expectancy of patients with immunosuppression and comorbidities. Infections …

The recent epidemic caused by aerosolized SARS-CoV-2 virus illustrates the importance
and vulnerability of the mucosal epithelial barrier against infection. Antimicrobial proteins …

Introduction CXCL17 is a mucosally secreted protein, and the most recently identified
human chemokine, an assignment based on protein fold prediction and chemotactic activity …

Chemokines are a group of secreted small molecules which are essential for cell migration
in physiological and pathological conditions by binding to specific chemokine receptors …

Oropharyngeal candidiasis (OPC) is a mucosal infection caused by Candida spp., and it is
common among the immunocompromised. This condition is mainly treated using oral …

The necessity to move away from conventional antibiotic therapy has sparked interest in
antimicrobial peptides (AMPs). One fascinating example is human CCL-28 chemokine …

Oropharyngeal candidiasis (OPC), commonly known as 'thrush', is an oral infection that
usually dismantles oral mucosal integrity and malfunctions local innate and adaptive …

Plasmid DNA (pDNA) represents a promising “genetic vaccine platform” capable of
overcoming major histocompatibility complex barriers. We previously demonstrated that low …

Classically, chemokines coordinate leukocyte trafficking during immune responses;
however, many chemokines have also been reported to possess direct antibacterial activity …

Candida species cause serious infections requiring prolonged and sometimes toxic therapy.
Antimicrobial proteins, such as chemokines, hold great interest as potential additions to the …