Ubiquitin and proteasomes in transcription
F Geng, S Wenzel, WP Tansey - Annual review of biochemistry, 2012 - annualreviews.org
Regulation of gene transcription is vitally important for the maintenance of normal cellular
homeostasis. Failure to correctly regulate gene expression, or to deal with problems that …
homeostasis. Failure to correctly regulate gene expression, or to deal with problems that …
Transcriptional regulation by histone ubiquitination and deubiquitination
Y Zhang - Genes & development, 2003 - genesdev.cshlp.org
Ubiquitin (Ub) is a 76-amino acid protein that is ubiquitously distributed and highly
conserved throughout eukaryotic organisms. Whereas the extreme C-terminal four amino …
conserved throughout eukaryotic organisms. Whereas the extreme C-terminal four amino …
Transcription-associated histone modifications and cryptic transcription
M Smolle, JL Workman - Biochimica et Biophysica Acta (BBA)-Gene …, 2013 - Elsevier
Eukaryotic genomes are packaged into chromatin, a highly organized structure consisting of
DNA and histone proteins. All nuclear processes take place in the context of chromatin …
DNA and histone proteins. All nuclear processes take place in the context of chromatin …
The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites
M G. Kapetanaki, J Guerrero-Santoro… - Proceedings of the …, 2006 - National Acad Sciences
Xeroderma pigmentosum (XP) is a heritable human disorder characterized by defects in
nucleotide excision repair (NER) and the development of skin cancer. Cells from XP group E …
nucleotide excision repair (NER) and the development of skin cancer. Cells from XP group E …
Genome-wide function of H2B ubiquitylation in promoter and genic regions
K Batta, Z Zhang, K Yen, DB Goffman… - Genes & …, 2011 - genesdev.cshlp.org
Nucleosomal organization in and around genes may contribute substantially to
transcriptional regulation. The contribution of histone modifications to genome-wide …
transcriptional regulation. The contribution of histone modifications to genome-wide …
Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability
MB Chandrasekharan, F Huang… - Proceedings of the …, 2009 - National Acad Sciences
The mechanism by which ubiquitination of histone H2B (H2Bub1) regulates H3-K4 and-K79
methylation and the histone H2A-H2B chaperone Spt16-mediated nucleosome dynamics …
methylation and the histone H2A-H2B chaperone Spt16-mediated nucleosome dynamics …
Histone ubiquitination: a tagging tail unfolds?
LJM Jason, SC Moore, JD Lewis, G Lindsey… - …, 2002 - Wiley Online Library
Despite the fact that histone H2A ubiquitination affects about 10–15% of this histone in most
eukaryotic cells, histone ubiquitination is among one of the less‐well‐characterized post …
eukaryotic cells, histone ubiquitination is among one of the less‐well‐characterized post …
Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation
MB Chandrasekharan, F Huang, ZW Sun - Epigenetics, 2010 - Taylor & Francis
Regulation of Set1-COMPASS-mediated H3K4 methylation and Dot1-mediated H3K79
methylation by H2BK123 ubiquitination (H2Bub1) is an evolutionarily conserved trans …
methylation by H2BK123 ubiquitination (H2Bub1) is an evolutionarily conserved trans …
Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis
Post-translational modifications (PTMs) of histones are an essential feature in the dynamic
regulation of chromatin. One of these modifications, ubiquitylation, has been speculated to …
regulation of chromatin. One of these modifications, ubiquitylation, has been speculated to …
H2B ubiquitylation: the end is in sight
MA Osley - Biochimica et Biophysica Acta (BBA)-Gene Structure …, 2004 - Elsevier
Historically, the first eukarytotic protein found to be modified by ubiquitin was H2A, originally
isolated from HeLa cells in 1975 by Harrison Busch and coworkers as a histone-like …
isolated from HeLa cells in 1975 by Harrison Busch and coworkers as a histone-like …