The protective role of antioxidants in the defence against ROS/RNS‐mediated environmental pollution

B Poljšak, R Fink - Oxidative medicine and cellular longevity, 2014 - Wiley Online Library
Overproduction of reactive oxygen and nitrogen species can result from exposure to
environmental pollutants, such as ionising and nonionising radiation, ultraviolet radiation …

Choking agents and chlorine gas–history, pathophysiology, clinical effects and treatment

T Zellner, F Eyer - Toxicology letters, 2020 - Elsevier
Introduction Choking agent exposure, among them chlorine gas, occurs in household or
industrial accidents, chemical warfare and terrorist attacks. Aims Review of published animal …

Toxic effects of chlorine gas and potential treatments: a literature review

S Achanta, SE Jordt - Toxicology mechanisms and methods, 2021 - Taylor & Francis
Chlorine gas is one of the highly produced chemicals in the USA and around the world.
Chlorine gas has several uses in water purification, sanitation, and industrial applications; …

[HTML][HTML] Formation of chlorinated lipids post-chlorine gas exposure

DA Ford, J Honavar, CJ Albert, MA Duerr, JY Oh… - Journal of lipid …, 2016 - ASBMB
Exposure to chlorine (Cl 2) gas can occur during accidents and intentional release
scenarios. However, biomarkers that specifically indicate Cl 2 exposure and Cl 2-derived …

Halogen-induced chemical injury to the mammalian cardiopulmonary systems

DR Addis, S Aggarwal, A Lazrak, T Jilling… - …, 2021 - journals.physiology.org
The halogens chlorine (Cl2) and bromine (Br2) are highly reactive oxidizing elements with
widespread industrial applications and a history of development and use as chemical …

[HTML][HTML] N-acetyl cysteine mitigates lung damage and inflammation after chlorine exposure in vivo and ex vivo

Å Gustafson, L Elfsmark, T Karlsson… - Toxicology and Applied …, 2023 - Elsevier
The objective of this study was to explore the effects of antioxidant treatments, specifically N-
acetylcysteine (NAC) and N-acetylcysteine amide (NACA), in a mouse model of chlorine (Cl …

Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury

A Lazrak, J Creighton, Z Yu… - … of Physiology-Lung …, 2015 - journals.physiology.org
Chlorine (Cl2) inhalation induces severe oxidative lung injury and airway
hyperresponsiveness (AHR) that lead to asthmalike symptoms. When inhaled, Cl2 reacts …

[HTML][HTML] Phosgene inhalation causes hemolysis and acute lung injury

S Aggarwal, T Jilling, S Doran, I Ahmad, JE Eagen… - Toxicology letters, 2019 - Elsevier
Abstract Phosgene (Carbonyl Chloride, COCl 2) remains an important chemical
intermediate in many industrial processes such as combustion of chlorinated hydrocarbons …

An Official American Thoracic Society Workshop Report: chemical inhalational disasters. Biology of lung injury, development of novel therapeutics, and medical …

EM Summerhill, GW Hoyle, SE Jordt… - Annals of the …, 2017 - atsjournals.org
This report is based on the proceedings from the Inhalational Lung Injury Workshop jointly
sponsored by the American Thoracic Society (ATS) and the National Institutes of Health …

Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation

A Jurkuvenaite, GA Benavides, S Komarova… - Free radical biology and …, 2015 - Elsevier
The mechanisms of toxicity during exposure of the airways to chlorinated biomolecules
generated during the course of inflammation and to chlorine (Cl 2) gas are poorly …