In situ self-assembly—the in situ formation of complex materials via biochemical reactions of
monomers—has enhanced the efficacy of drug delivery for cancer therapy and imaging. So …

Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

Natural enzymes usually suffer from high production cost, ease of denaturation and
inactivation, and low yield, making them difficult to be broadly applicable. As an emerging …

Wound healing is a long‐term, multistage biological process that includes hemostasis,
inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide …

Non-invasive visualization of dynamic molecular events in real-time via molecular imaging
may enable the monitoring of cascade catalytic reactions in living systems, however effective …

Optical nanoparticles are promising diagnostic tools; however, their shallow optical imaging
depth and slow clearance from the body have impeded their use for in vivo disease …

Nanomedicines are attractive paradigms to deliver drugs, contrast agents,
immunomodulators, and gene editors for cancer therapy and diagnosis. However, the …

The physical morphologies of nanoparticles, especially size and shape, always significantly
influence their biological behaviors. In the past, nanoparticles with constant physical …

Bioorthogonal chemistry is a powerful tool to site-specifically activate drugs in living systems.
Bioorthogonal reactions between a pair of biologically reactive groups can rapidly and …